ATP-binding sites in the membrane components of histidine permease, a periplasmic transport system.
ATP-binding sites in the membrane components of histidine permease, a periplasmic transport system.
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组氨酸通透酶（一种周质转运系统）膜成分中的 ATP 结合位点。
DOI：
10.1073/pnas.81.23.7333
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发表时间：
1984
影响因子：
11.1
通讯作者：
Ames,GF
中科院分区：
文献类型：
--
作者：
Hobson,AC;Weatherwax,R;Ames,GF
Two components of the histidine permease in Salmonella typhimurium, the membrane-bound P and M proteins, react with the photoaffinity labeling reagent 8-azido-ATP in isolated membranes. The extent of labeling is decreased by the addition of ATP and somewhat less by addition of GTP, CTP, UTP, and ADP. Cyclic AMP, NAD, FAD, and S-adenosylmethionine have little effect. We propose that one or both of these proteins have a site capable of binding an adenine nucleotide and that, therefore, they may be involved in the energy-coupling step in active transport.
