Genetic content of Influenza H 3 N 2 vaccine seeds
Genetic content of Influenza H 3 N 2 vaccine seeds
复制标题
H 3 N 2 流感疫苗种子的基因含量
DOI:
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复制
发表时间:
2017
期刊:
影响因子:
--
通讯作者:
Bergeron
中科院分区:
文献类型:
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作者:
Corinne Bergeron;bruno Lina Martine VALETTE;M. Ottmann;Bergeron
Influenza vaccine seeds produced in chicken eggs are selected through HA and NA surface glycoproteins antigenicity, as well as through high replicative ability. Here we characterize the genetic content of recently used thirteen H3N2 influenza vaccine seeds. Interestingly, sequence analysis of the vaccine seeds shows reassortment events leading to PR8:H3N2 segment constellations, ranging from the 6:2 to 2:6 constellations. This study shows that the H3N2 PB1 is the most frequent internal segment incorporated in the tested vaccines seeds.
影响因子:
5.5
作者:
Liu, Jonathan;Shi, Xiao;Kemble, George
通讯作者:
Kemble, George
DOI:
10.1292/jvms.61.987
发表时间:
1999
期刊:
The Journal of veterinary medical science
影响因子:
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作者:
Ito,T;Kawaoka,Y;Ohira,M;Takakuwa,H;Yasuda,J;Kida,H;Otsuki,K
通讯作者:
Otsuki,K