NTDB: Thermodynamic Database for Nucleic Acids, Version 2.0
NTDB: Thermodynamic Database for Nucleic Acids, Version 2.0
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DOI：
10.1093/nar/gkg114
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发表时间：
2003-01-01
影响因子：
14.9
通讯作者：
Au-Yeung, SCF
中科院分区：
文献类型：
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作者：
Chiu, WLAK;Sze, CN;Au-Yeung, SCF
核酸热力学数据库的第二个版本NTDB 2.0包括超过4600个条目（比1.0版增加了250%）。它包含序列类型和几个热力学参数（焓，Δ H;熵，Δ H;吉布斯自由能，Δ H;熔化温度，T-m）的细节，用于提取热力学参数的实验模型和方法，缓冲条件以及所有相关的文献信息。此外，还包括与NTDB相关的数据库统计数据和参考文献。关于正常和修饰的核碱基和核苷的信息收集在新的核苷部分中，迄今为止收集的数据将在NTDB 2.0中发布。NTDB可在http：/ / ntdb上免费获得。香港中文大学化学edu. HK.
The second release of Thermodynamic Database for Nucleic Acids, NTDB 2.0, includes more than 4600 entries ( 250% increase over release 1.0). It contains sequence types and details of several thermodynamic parameters ( enthalpy, DeltaH; entropy, DeltaH; Gibbs free energy, DeltaH; melting temperature, T-m), experimental models and methods for extracting thermodynamic parameters, buffer conditions as well as all relevant literature information. I addition, the database statistics and references related to NTDB are included. Information on normal and modified nucleobases and nucleosides are collected in a new section Nucleoside whereby data collected thus far will be release in NTDB 2.0. The NTDB is freely available at http: / / ntdb. chem. cuhk. edu. hk.