PHYSICAL-ACTIVITY AND CORONARY HEART-DISEASE IN MIDDLE-AGED AND ELDERLY MEN - THE HONOLULU-HEART-PROGRAM
PHYSICAL-ACTIVITY AND CORONARY HEART-DISEASE IN MIDDLE-AGED AND ELDERLY MEN - THE HONOLULU-HEART-PROGRAM
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DOI：
10.2105/ajph.78.6.683
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发表时间：
1988-06-01
影响因子：
12.7
通讯作者：
YANO, K
中科院分区：
文献类型：
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作者：
DONAHUE, RP;ABBOTT, RD;YANO, K
对参加檀香山心脏计划的中年男性(45岁-)和老年男性(65-69岁)的体力活动与冠心病发生的关系进行了研究。经过12年的随访，结果表明，在两个年龄组中，研究开始时体力活动水平的增加与明确的冠心病风险呈负相关。特别是，在那些年龄在45岁到之间的人中，生活方式活跃的男性的冠心病确诊率比不活跃的男性低30%(反应性风险，0.69；95%可信区间，0.53，0.88)。在那些年龄在以上的人中，活跃男性的冠心病确诊率不到久坐生活方式者的一半(相对风险为0.43；95%可信区间为0.19)。0.99)。在控制了几个心血管风险因素和潜在的混杂变量后，这些结果继续有效，支持了早先的观察结果，即体力活动对中年有益，并进一步表明，这种好处可能也适用于老年男性人群。
The relationship of physical activity to the development of definite coronary heart disease was examined separately in middle-aged (45-64 years) and elderly men (65-69 years) participating in the Honolulu Heart Program. After 12 years of follow-up, results indicate that increased levels of physical activity repoorted at study entry were inversely related to the risk of definite coronary heart disease in both age groups. In particular, among those aged 45 to 64 years, the rate of definite coronary heart disease in men who led active life styles was 30 per cent lower than the rate experienced by those who were less active (reactive risk, 0.69; 95% confidence interval, 0.53, 0.88). In those older than 64 years, the rate of definite coronary heart disease in active men was less than half the rate experienced by those who led more sedentary life styles (relative risk 0.43; 95% CI, 0.19. 0.99). These results continued to hold up when controlling for several cardiovascular risk factors and potentially confounding variables, supporting earlier observations that physical activity is beneficial in middle-age and further suggesting that benefits may extend to the elderly male population as well.