Prenatal effects of ethanol on the behavioral development of the rat
Prenatal effects of ethanol on the behavioral development of the rat
复制标题
产前乙醇对大鼠行为发育的影响
DOI：
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发表时间：
1978
期刊：
影响因子：
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通讯作者：
G. Kirouac
中科院分区：
文献类型：
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作者：
M. Demers;G. Kirouac
妊娠雌性大鼠从妊娠第5天至第18天每日静脉输注乙醇。其他雌性动物接受生理盐水输注或未接受处理。在出生时，这些后代被寄养在未经治疗的母亲身边，研究他们的行为发育，直到他们21天大。对三组受试者进行了14项神经运动发育测试，以比较他们的行为成熟速度。结果表明，在怀孕期间接受乙醇的母亲所生的动物往往行为发育缓慢：在14次测试中，有8次测试中，它们达到性能标准的时间明显较晚。
Pregnant female rats received daily intravenous ethanol infusions from Day 5 to Day 18 of pregnancy. Other females received saline infusions or no treatments. At birth, the offspring were fostered to nontreated mothers, and their behavioral development was studied until they were 21 days old. Fourteen tests of neuromotor development were administered to the subjects in the three groups in order to compare their speed of behavioral maturation. The results indicated that the animals born to mothers that received ethanol during pregnancy tended to have a slow behavioral development: in 8 out of 14 tests, they reached the performance criterion significantly later.