Validation of the Center for Epidemiologic Studies Depression Scale in screening for major depressive disorder among retired firefighters exposed to the World Trade Center disaster
Validation of the Center for Epidemiologic Studies Depression Scale in screening for major depressive disorder among retired firefighters exposed to the World Trade Center disaster
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DOI：
10.1016/j.jad.2009.05.028
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发表时间：
2010-03-01
影响因子：
6.6
通讯作者：
Prezant, David J.
中科院分区：
文献类型：
--
作者：
Chiu, Sydney;Webber, Mayris P.;Prezant, David J.
研究背景：我们评估了2005年12月至2007年7月在世界贸易中心（WTC）暴露的纽约消防局（FDNY）退休消防员中，采用改良的流行病学研究中心抑郁量表（CES-D-m）与诊断性访谈时间表（DIS）识别重度抑郁障碍（MDD）的性能。FDNY在其医疗诊断和治疗计划中招募了退休消防员。所有参与者在同一天完成了CES-D-m和DIS。采用多因素Logistic回归分析方法对CES-D-m进行多因素分析。的1915名退休男性消防员使用DIS诊断为MDD。使用最常见的CES-D截止评分16，风险升高的患病率为36%，使用截止评分22下降至23%，由尤登指数确定为22. CES-D-m敏感性为0.84，特异性为0.82，ROC曲线下面积相对于DIS MDD诊断为0.89局限性参与者比非参与者更有可能生活在纽约市地区结论这是第一个对WTC救援/恢复工作者进行的评估一个月版CES-D性能的研究。我在识别高风险人群方面表现出色由于诊断随访耗时且成本高昂，因此使用已在研究人群中验证的筛查工具正确区分高风险人群非常重要（C）2009 Elsevier B V保留所有权利
Background We evaluated the performance of a modified Center of Epidemiologic Studies Depression Scale (CES-D-m), which captured symptoms in the past month, in comparison to the Diagnostic Interview Schedule (DIS) in identification of major depressive disorder (MDD) in World Trade Center (WTC)-exposed retired Fire Department, City of New York (FDNY) firefighters Methods From 12/2005 to 7/2007. FDNY enrolled retired firefighters in its Medical Monitonrig and Treatment Program All participants completed the CES-D-m and the DIS on the same day Sensitivity, specificity, receiver operating characteristic (ROC) Curves, and Youden's index were used to assess properties of the CES-D-m Multivariate logistic regression analyses were also used Results 7% of 1915 retired male firefighters were diagnosed with MDD using the DIS Using the most common CES-D cutoff score of 16, the prevalence of elevated risk was 36%, which declined to 23% using a cutoff score of 22, as determined by Youden's index At 22. CES-D-m sensitivity was 0 84, specificity was 0 82,and the area under the ROC curve was 0 89 relative to DIS MDD diagnosis Limitations Participants were more likely than non-participants to live in the New York City area Conclusions This is the first study of WTC rescue/recovery workers to assess the performance of a one-month version of the CES-D The CES-D-m performed well in identifying those at elevated risk Since diagnostic follow-up is time consuming and costly, it is important to correctly distinguish those at elevated risk using a screening tool that has been validated in the Population under Study (C) 2009 Elsevier B V All rights reserved