Quality analysis of randomized controlled trials in the International Journal of Impotence Research: quality assessment and relevant clinical impact
Quality analysis of randomized controlled trials in the International Journal of Impotence Research: quality assessment and relevant clinical impact
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DOI：
10.1038/ijir.2016.48
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发表时间：
2017-03-01
影响因子：
2.6
通讯作者：
Lee, S. W.
中科院分区：
文献类型：
--
作者：
Kim, K. S.;Jo, J. K.;Lee, S. W.
对发表在《国际阳痿研究杂志》（IJIR）上的随机对照试验（rct）的质量进行了分析。1997-2014年在IJIR上发表的报告rct的原始文章由PubMed确定。采用Jadad量表、van Tulder量表和Cochrane Collaboration Risk of Bias Tool评估其方法学质量。评审期分为前期（1997-2002年）、中期（2003-2008年）和后期（2009-2014年）三个阶段。评估研究对象和机构审查委员会批准、干预、资助和适当分配对RCT质量的影响。IJIR发表RCT的频率在19年的研究期间没有变化。Cochrane Collaboration risk of bias Tool的前、中、后期低偏倚风险文章数分别为1篇（3.0%）、2篇（4.4%）和4篇（12.1%）（P=0.04）。高质量低偏倚风险的RCT发表频率随时间增加。干预和资金显著影响RCT的质量。因此，随着时间的推移，在IJIR上发表的随机对照试验的数量保持不变，而它们的质量却有所提高。正在进行的扩大随机对照试验数量和进一步提高IJIR发表的研究质量的努力将改善临床实践。
The quality of randomized controlled trials (RCTs) reported in the International Journal of Impotence Research (IJIR) was analyzed. The original articles that reported RCTs and were published in the IJIR in 1997-2014 were identified by PubMed. Their methodological quality was assessed using the Jadad scale, van Tulder scale and Cochrane Collaboration Risk of Bias Tool. The review period was divided into three periods: early (1997-2002), mid (2003-2008) and late (2009-2014). The effect of study subject and presence of Institutional Review Board approval, intervention, funding and adequate allocation concealment on RCT quality was assessed. The frequency of RCT publication in the IJIR did not change over the 19-year study period. Numbers of low risk of bias articles were 1 (3.0%), 2 (4.4%) and 4 (12.1%) in the early, mid and late periods in Cochrane Collaboration Risk of Bias Tool (P=0.04). High-quality low risk of bias RCT publication frequency increased over time. Intervention and funding significantly influenced RCT quality. Thus, the number of RCTs published in the IJIR over time has remained constant while their quality has improved. Ongoing efforts to expand the numbers of RCTs and further improve the quality of research published by the IJIR will improve clinical practice.