Risk factors for shigellosis in Thailand
Risk factors for shigellosis in Thailand
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DOI：
10.1016/j.ijid.2006.05.011
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发表时间：
2006-11-01
影响因子：
8.4
通讯作者：
Chaicumpa, Wanpen
中科院分区：
文献类型：
--
作者：
Chompook, Pornthip;Todd, Jim;Chaicumpa, Wanpen
目的：为了评估志贺菌病的潜在危险因素，包括家蝇density.Methods：匹配的病例对照研究，调查志贺菌病的潜在危险因素进行了半城市地区，Kaengkhoi区，萨拉布里省，泰国中部。志贺菌病例是从一项为期两年的以人群为基础的监测研究中确定的，该研究检测了该地区的腹泻和志贺菌病。该研究评估了广泛的暴露，并使用条件logistic回归分析，通过调整社会经济地位的代理标记（家庭收入和居住类型）的比值比（OR）进行评估。卫生行为，如定期洗手（p < 0.05），家庭周围环境清洁（p < 0.001）和有水冲厕所（p = 0.08）与多变量模型中志贺氏菌病风险降低相关。相反，表明高于平均社会经济地位的因素，如不得不租房而不是拥有住房（p < 0.001）和低家庭收入（p < 0.01）与志贺氏菌病的风险增加有关。对于儿童，母乳喂养在降低志贺氏菌病风险方面显示出强保护作用（p < 0.01）。在调整环境因素之前，厨房区域的苍蝇密度与志贺氏菌病风险增加相关（p < 0.01）。结论：我们发现社会经济地位与志贺氏菌病风险之间存在相关性。为了减少这种情况下的志贺氏菌病，我们建议重点关注三个方面的干预措施：改善供水和卫生设施（特别是厕所和垃圾处理），包括控制苍蝇，洗手的健康教育，以及促进母乳喂养。(c)2006年国际传染病学会。由Elsevier Ltd.出版，版权所有。
Objectives: To assess the potential risk factors for shigellosis including housefly density.Methods: A matched case-control study to investigate potential risk factors for shigellosis was conducted in a semi-urban area, Kaengkhoi District, Saraburi Province, central Thailand. Shigello cases were ascertained from a two-year population-based surveillance study detecting diarrhea and shigellosis in the area. The study evaluated a wide range of exposures, which were assessed by odds ratios (OR) adjusted for proxy markers of socioeconomic status: family income, and type of residence, using conditional logistic regression analysis.Results: Hygiene behaviors such as regular hand washing (p < 0.05), a clean environment surrounding the household (p < 0.001), and the availability of water to flush the toilet (p = 0.08) were associated with a reduced risk for shigellosis in the multivariate model. In contrast factors indicating a tower than average socioeconomic status, such as having to rent instead of owning one's housing (p < 0.001) and a low family income (p < 0.01) were associated with an increased risk for shigellosis. For children, breastfeeding showed a strong protective effect in reducing the risk of shigellosis (p < 0.01). Prior to adjustment for environmental factors, fly density in the kitchen area was associated with an increased risk of shigellosis (p < 0.01).Conclusions: We found a correlation between socioeconomic status and the risk for shigellosis. To reduce shigellosis in this setting, we recommend interventions focused on three aspects: improved water supply and sanitation (especially latrines and garbage disposal) including fly control, health education on hand washing, and the promotion of breastfeeding. (c) 2006 International Society for Infectious Diseases. Published by Elsevier Ltd. Ail rights reserved.