The effect of regression to the mean in epidemiologic and clinical studies.

The effect of regression to the mean in epidemiologic and clinical studies.
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流行病学和临床研究中均值回归的影响。

DOI:
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发表时间:
1976
影响因子:
5
通讯作者:
C. Davis
C. Davis
中科院分区:
医学2区
文献类型:
--
作者:
C. Davis

文献摘要

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在本文中,我们注意到回归到平均值的方法可以影响临床和流行病学研究中治疗效果的测量。很明显,回归可能具有相当大的影响,并可能导致有关治疗效果的错误结论。因此,这里概述的程序应该有助于在规划阶段以及分析时考虑回归。
In this paper, we have noted the ways in which regression to the mean can affect the measurement of treatment effects in clinical and epidemiologic studies. It is apparent that regression can have a sizeable effect and may lead to erroneous conclusions concerning treatment effects. Thus, the procedures outlined here should be useful in taking regression into account at the planning stage as well as at the time of analysis.