Backbone resonance assignments of the micro-RNA precursor binding region of human TRBP
Backbone resonance assignments of the micro-RNA precursor binding region of human TRBP
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DOI：
10.1007/s12104-012-9416-8
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发表时间：
2013-10-01
影响因子：
0.9
通讯作者：
Plevin, Michael J.
中科院分区：
文献类型：
--
作者：
Benoit, Matthieu P. M. H.;Plevin, Michael J.
TAR-RNA binding protein (TRBP) is a multidomain human protein involved in micro-RNA (miRNA) biogenesis. TRBP is a component of both the Dicer complex, which processes precursor miRNAs, and the RNA-induced silencing complex-loading complex. In addition, TRBP is implicated in the human immunodeficiency virus replication cycle and interferon-protein kinase R activity. TRBP contains 3 double-stranded RNA binding domains the first two of which have been shown to interact with miRNA precursors. Here we present the backbone resonance assignments and secondary structure of residues 19-228 of human TRBP2.
