Generating samples under a Wright-Fisher neutral model of genetic variation
Generating samples under a Wright-Fisher neutral model of genetic variation
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DOI：
10.1093/bioinformatics/18.2.337
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发表时间：
2002-02-01
期刊：
影响因子：
5.8
通讯作者：
Hudson, RR
中科院分区：
文献类型：
--
作者：
Hudson, RR
有一个蒙特卡罗计算机程序可用于生成根据赖特 - 费希尔中性模型进化的群体的样本。该程序假定一个无限位点突变模型，并允许重组、基因转换、亚群体之间的对称迁移以及各种人口统计学历史。所生成的样本可用于研究在这些中性模型下任何样本统计量的抽样特性。
A Monte Carlo computer program is available to generate samples drawn from a population evolving according to a Wright-Fisher neutral model. The program assumes an infinite-sites model of mutation, and allows recombination, gene conversion, symmetric migration among subpopulations, and a variety of demographic histories. The samples produced can be used to investigate the sampling properties of any sample statistic under these neutral models.