[Pertussis in young infants].
[Pertussis in young infants].
复制标题
[小婴儿百日咳]。
DOI：
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发表时间：
1998
影响因子：
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通讯作者：
S. Geelen
中科院分区：
文献类型：
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作者：
A. L. Vegelin;A. Vught;T. Wolfs;J. Kimpen;S. Geelen
四名婴儿，三名分别为4周、2.5个月和3个月大的女孩，以及一名2个月大的男孩，因严重呼吸困难而住院。其中两名患者出现呼吸暂停、心动过缓和缺氧，其中一名患者还出现抽搐，另外两名患者出现支气管肺炎，其中一名患者最终死亡。所有人都患有百日咳。在百日咳爆发期间，6 个月以下的婴儿患严重疾病的风险最高。然而，在这个年龄段，百日咳的临床症状往往不典型。可能不会出现阵发性咳嗽和大声喘息等典型症状，但可能会出现喂养问题、呼吸暂停、发绀和心动过缓。对于 6 个月以下的婴儿，如果出现百日咳迹象，则需要住院治疗。根据荷兰目前的疫苗接种计划，婴儿在 3、4、5 和 11 个月大时接种疫苗。从 1999 年开始，第一次疫苗接种将在 2 个月大时进行。
Four infants, three girls aged 4 weeks, 2.5 months and 3 months, and a boy aged 2 months, were hospitalized because of severe respiratory distress. Apnoea spells with bradycardia and hypoxia were seen in two of the patients, one showing convulsions as well, and bronchopneumonia in the other two, of whom one eventually died. All suffered from pertussis. During outbreaks of pertussis, infants less than 6 months of age are at highest risk for severe disease. In this age group, however, the clinical signs of pertussis are often atypical. Classical symptoms such as paroxysms of cough and loud whoops may be absent while feeding problems, apnoea, cyanosis and bradycardia may be present. For infants younger than 6 months with signs indicating pertussis hospitalization is indicated. In the current vaccination schedule in the Netherlands infants are vaccinated at 3, 4, 5 and 11 months of age. Starting in 1999 the first vaccination will be administered at the age of 2 months.