Waist circumference, dual-energy X-ray absortiometrically measured abdominal adiposity, and computed tomographically derived intra-abdominal fat area on detecting metabolic risk factors in obese women
Waist circumference, dual-energy X-ray absortiometrically measured abdominal adiposity, and computed tomographically derived intra-abdominal fat area on detecting metabolic risk factors in obese women
复制标题
DOI：
10.1016/j.nut.2008.03.004
复制
发表时间：
2008-07-01
期刊：
影响因子：
4.4
通讯作者：
Kim, Yun-Jin
中科院分区：
文献类型：
--
作者：
Lee, Kayoung;Lee, Sangyeoup;Kim, Yun-Jin
目的：我们调查了哪些腹部肥胖测量、腰围 (WC)、双能 X 射线吸收测定法 (DXA) 测量的腹部脂肪以及计算机断层扫描 (CT) 得出的腹内脂肪面积 (IAF) 在识别代谢危险因素方面最具预测性。方法：95 名韩国女性（体重指数 27.5 +/- 3.2 kg/m(2)，WC 90.2 +/- 6.8本研究对体重 42 +/- 10.6 岁、腹部肥胖（WC >= 80 厘米）的受试者进行了检查。使用 DXA（躯干和机器人脂肪的绝对值和百分比、躯干与腿部脂肪比率以及机器人与雌性脂肪比率）和 CT（IAF 以及 IAF 与皮下腹部脂肪 [SAF] 的比率）评估腹部肥胖情况。代谢指标为血压、高密度脂蛋白胆固醇、三酰甘油、空腹血糖、胰岛素、高敏C反应蛋白。代谢综合征 (MS) 定义为存在以下至少两项：三酰甘油水平 >= 150 mg/dL、高密度脂蛋白胆固醇水平 = 130/85 mmHg 和/或空腹血糖水平 >= 100 mg/dL。 结果：与绝经后女性相比，绝经前女性的肥胖测量值与代谢指标之间的相关性更强。 MS 和所有腹部肥胖测量值（WC、DXA 测量的腹部脂肪和 CT 得出的 IAF）的曲线下面积均显着。曲线下面积在测量之间没有显着差异。每次腹部脂肪测量的阈值预测 MS 的敏感性和特异性分别为 38-93% 和 34-96%。腹部脂肪含量高 1 SD 的女性患 MS 的可能性高出 1.6-3.4 倍。 结论：没有任何一项腹部脂肪测量（即 WC、DXA 测量的腹部脂肪和 CT 评估的 IAF）比其他测量更能预测代谢危险因素。 (C) 2008 Elsevier Inc. 保留所有权利。
Objectives: We investigated which abdominal adiposity measurements, waist circumference (WC), dual-energy X-ray absorptiometry (DXA)-measured abdominal fat, and computed tomography (CT)-derived intra-abdominal fat areas (IAF), were the most predictive in identifying metabolic risk factors.Methods: Ninety-five Korean women (body mass index 27.5 +/- 3.2 kg/m(2), WC 90.2 +/- 6.8 cm, age 42 +/- 10.6 y) with abdominal obesity (WC >= 80 cm) were examined in this study. Abdominal adiposity was assessed using DXA (absolute values and percentages of trunk and android fat, trunk-to-leg fat ratio, and android-to-gynoid fat ratio) and CT (IAF and ratio of IAF to subcutaneous abdominal fat [SAF]). Metabolic indicators were blood pressure, high-density lipoprotein cholesterol, triacylglycerol, fasting glucose, insulin, and high-sensitivity C-reactive protein. Metabolic syndrome (MS) was defined as the presence of at least two of the following: triacylglycerol level >= 150 mg/dL, high-dcnsity lipoprotein cholesterol level = 130/85 mmHg, and/or fasting glucose level >= 100 mg/dL.Results: The correlations between adiposity measurements and metabolic indicators were stronger in premenopausal compared with postmenopausal women. Areas under the curve for MS and all abdominal adiposity measurements (WC, DXA-measured abdominal fat, and CT-derived IAF) were significant. Areas under the curve were not significantly different among measurements. The sensitivity and specificity at the threshold value of each abdominal adiposity measurement to predict MS were 38-93% and 34-96%, respectively. Women with 1 SD higher abdominal adiposity were 1.6-3.4 times more likely to have MS.Conclusion: No single abdominal adiposity measurement, i.e., WC, DXA-measured abdominal fat, and CT-assessed IAF, was a stronger predictor of metabolic risk factors than the other. (C) 2008 Elsevier Inc. All rights reserved.