Xmipp 3.0: An improved software suite for image processing in electron microscopy

Xmipp 3.0: An improved software suite for image processing in electron microscopy
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DOI:
10.1016/j.jsb.2013.09.015
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发表时间:
2013-11-01
影响因子:
3
通讯作者:
Sorzano, C. O. S.
Sorzano, C. O. S.
中科院分区:
生物学3区
文献类型:
--
作者:
de la Rosa-Trevin, J. M.;Oton, J.;Sorzano, C. O. S.

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XMIPP是电子显微镜图像处理的专用软件包,主要专注于通过单颗粒分析进行大分子的3D重建。在本文中,我们将介绍XMIPP 3.0,这是一个主要版本,它在以前的版本上引入了几项改进和新的开发。一个主要的改进是项目的概念,它存储了从数据导入到最终结果的整个处理工作流。现在可以监控、重现和重新启动所有计算任务,并以图形方式探索与给定项目相关的一整套相关任务。其他图形工具也得到了改进,如数据可视化,粒子拾取和参数“向导”,允许视觉选择一些关键参数。许多标准的图像格式是透明地支持从所有程序的输入/输出。此外,结果已经标准化,促进了不同Xmipp程序之间的互操作。最后,由于大量的代码重构,底层C++库更适合未来的开发,所有代码都得到了优化。XMIPP是一个开源软件包,可从http://xmipp.cnb.csic.es免费下载。(C)2013 Elsevier Inc. All rights reserved.
Xmipp is a specialized software package for image processing in electron microscopy, and that is mainly focused on 3D reconstruction of macromolecules through single-particles analysis. In this article we present Xmipp 3.0, a major release which introduces several improvements and new developments over the previous version. A central improvement is the concept of a project that stores the entire processing workflow from data import to final results. It is now possible to monitor, reproduce and restart all computing tasks as well as graphically explore the complete set of interrelated tasks associated to a given project. Other graphical tools have also been improved such as data visualization, particle picking and parameter "wizards" that allow the visual selection of some key parameters. Many standard image formats are transparently supported for input/output from all programs. Additionally, results have been standardized, facilitating the interoperation between different Xmipp programs. Finally, as a result of a large code refactoring, the underlying C++ libraries are better suited for future developments and all code has been optimized. Xmipp is an open-source package that is freely available for download from: http://xmipp.cnb.csic.es. (C) 2013 Elsevier Inc. All rights reserved.