Evolution of the regionalization and patterning of the vertebrate telencephalon: what can we learn from cyclostomes?
Evolution of the regionalization and patterning of the vertebrate telencephalon: what can we learn from cyclostomes?
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DOI：
10.1016/j.gde.2013.02.008
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发表时间：
2013-08
影响因子：
4
通讯作者：
F. Sugahara;Y. Murakami;N. Adachi;S. Kuratani
中科院分区：
文献类型：
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作者：
F. Sugahara;Y. Murakami;N. Adachi;S. Kuratani
端脑是脊椎动物中枢神经系统（CNS）的最前部，是脊椎动物机体的高度多样化区域。其进化起源仍然难以捉摸，特别是关于其结构的祖先状态以及端脑特异性神经元亚型的起源。圆口类（七鳃鳗和八目鳗）是有颌类（有颌脊椎动物）的姐妹类群，是研究脊椎动物中枢神经系统进化的重要模式动物。在这里，我们总结了最近关于七鳃鳗端脑发育的研究。通过比较详细的哺乳动物的发育研究，我们说明了一个可能的祖先的发展计划的脊椎动物端脑的多样化的基础上，并提出了可能的方法来了解端脑的早期进化。
The telencephalon, the most anterior part of the vertebrate central nervous system (CNS), is a highly diversified region of the vertebrate body. Its evolutionary origin remains elusive, especially with regard to the ancestral state of its architecture as well as the origin of telencephalon-specific neuron subtypes. Cyclostomes (lampreys and hagfish), the sister group of the gnathostomes (jawed vertebrates), serve as valuable models for studying the evolution of the vertebrate CNS. Here, we summarize recent studies on the development of the telencephalon in the lamprey. By comparing detailed developmental studies in mammals, we illustrate a possible ancestral developmental plan underlying the diversification of the vertebrate telencephalon and propose possible approaches for understanding the early evolution of the telencephalon.