Ossification of the Posterior Longitudinal Ligament of the Spine

Ossification of the Posterior Longitudinal Ligament of the Spine
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DOI:
10.1097/00003086-198404000-00010
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发表时间:
1984-04
影响因子:
4.2
通讯作者:
N. Tsuyama
N. Tsuyama
中科院分区:
医学2区
文献类型:
--
作者:
N. Tsuyama

文献摘要

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脊柱后纵韧带骨化(OPLL)是一个新认识的实体。由于这种疾病在日本的发病率异常高,日本公共卫生和福利部成立了一个特别委员会来调查这种令人困惑的疾病;自1975年以来,该委员会对日本2100名OPLL患者进行了深入研究。该小组在日本和东亚国家进行了一项流行病学研究。描述了该病引起的症状和残疾。x线表现分为连续型、节段型、混合型和局部性。描述了胸腰椎水平的OPLL并黄韧带骨化,并强调了脊髓损伤的风险以及断层扫描和计算机断层扫描的重要性。没有得出关于病因的结论,但常见的发现包括全身性骨质增生倾向、糖代谢异常倾向和低肠内钙吸收。注意到遗传发生率相对较高。本文介绍了保守和手术治疗方法,特别是椎管拓宽手术。
Ossification of the posterior longitudinal ligament of the spine (OPLL) is a newly recognized entity. As the incidence of this disease was exceptionally high in Japan, the Japanese Ministry of Public Health and Welfare instituted a special commission for the investigation of this perplexing disease; since 1975 this committee has performed an intensive study of 2100 patients with OPLL in Japan. An epidemiologic study was conducted by this group in Japan and in eastern Asiatic countries. Symptoms and disabilities caused by the disease were described. Roentgenographic findings were classified as continuous, segmental, mixed, or localized. OPLL at the thoracic and lumbar levels combined with ossification of the yellow ligament was described, and the risk of spinal cord damage as well as the importance of tomography and computerized tomographic scanning were stressed. No conclusions were reached concerning etiology, but common findings included a generalized hyperostotic tendency, a tendency for abnormal glucose metabolism, and low enteral calcium absorption. A relatively high hereditary occurrence was noted. Conservative and surgical treatment methods were described, with particular reference to spinal canal-widening operations.