Multiobjective Optimization of an Electrostimulative Acetabular Revision System
Multiobjective Optimization of an Electrostimulative Acetabular Revision System
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DOI：
10.1109/tbme.2009.2030961
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发表时间：
2010-02-01
影响因子：
4.6
通讯作者：
van Rienen, Ursula
中科院分区：
文献类型：
--
作者：
Potratz, Carsten;Kluess, Daniel;van Rienen, Ursula
在本文中，我们提出了一种新的方法，通过电刺激髋臼区的骨增殖率的提高。基于该区域的复杂组织结构，使用基于髋臼区域的高分辨率计算机断层扫描的模型，通过数值方法计算电场分布。这导致复杂的、非线性的和离散的优化问题。因此，开发了一种自适应算法，以减少几个数量级的计算量。我们将该过程分为两个阶段：数据提取和随后的优化过程。所使用的优化算法利用进化的概念和多维定义的最优性不同，部分矛盾的目标函数。最后，我们提出了不同的刺激情况下的第一个优化结果。
In this paper, we present a new approach for the enhancement of the bone proliferation rate by electrostimulation in the acetabular region. Based on the complex tissue structure in this area, the electric field distributions were computed by numerical means using a model based on high-resolution computed tomography scans of the acetabular area. This results in a complex, nonlinear, and discrete optimization problem. Therefore, an adapted algorithm was developed to reduce the computational effort in the order of several magnitudes. We divided the procedure into two stages: data extraction and a subsequent optimization process. The used optimization algorithm utilizes an evolutionary concept and a multidimensional definition of optimality for different, partly contradictive objective functions. Finally, we present first optimization results for different stimulation situations.