2-and 3-Monohalogenated BODIPY Dyes and Their Functionalized Analogues: Synthesis and Spectroscopy
2-and 3-Monohalogenated BODIPY Dyes and Their Functionalized Analogues: Synthesis and Spectroscopy
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DOI：
10.1002/ejoc.201100324
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发表时间：
2011-08-01
影响因子：
2.8
通讯作者：
Dehaen, Wim
中科院分区：
文献类型：
--
作者：
Leen, Volker;Leemans, Tom;Dehaen, Wim
从适当卤代的酰基吡咯开始，可以获得宽范围的反应性4，4-二氟-4-硼杂-3a，4a-二氮杂-s-引达省（BODIPY）衍生物。荧光染料在亲核芳香取代、过渡金属催化的交叉偶联和铜催化的叠氮化物环加成（点击化学）中显示出优异的反应性。的光谱性质的起始和最终的二氟硼二吡咯-亚甲基作为其结构的函数进行了讨论。
Starting from appropriately halogenated acylpyrroles, a wide range of reactive 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) derivatives can be obtained. The fluorescent dyes display excellent reactivity in nucleophilic aromatic substitution, transition-metal-catalyzed cross-coupling and copper-catalyzed cycloaddition to azides (click chemistry). The spectral properties of the starting and final difluoroboron dipyrro-methenes are discussed as a function of their structure.