VAGAL MECHANORECEPTORS OF INFERIOR THORACIC ESOPHAGUS, LOWER ESOPHAGEAL SPHINCTER AND STOMACH IN SHEEP
VAGAL MECHANORECEPTORS OF INFERIOR THORACIC ESOPHAGUS, LOWER ESOPHAGEAL SPHINCTER AND STOMACH IN SHEEP
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DOI：
10.1007/bf00581145
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发表时间：
1978-01-01
影响因子：
4.5
通讯作者：
ROUSSEAU, JP
中科院分区：
文献类型：
--
作者：
FALEMPIN, M;MEI, N;ROUSSEAU, JP
在麻醉的幼羊结状神经节记录了60个感觉迷走神经元的单位活动。它们来自胸下食管（14个受体）、食管下括约肌（LES）（16个受体）和胃（30个受体）。位于胸下段食管的机械感受器被内脏的扩张和收缩激活。除1个受体在强烈扩张时产生开关效应外，其余均属于慢适应型。L.E.S.的机械感受器区与食管慢适应性终末十分相似。它们常表现为紧张性自发活动，有时受呼吸节律的调节。胃感受器分布在胃的不同部位：网胃、瘤胃、食管沟，但主要集中在食管沟、网胃后部和瘤胃前部。他们慢慢适应中度机械刺激（扩张和收缩），他们在某些情况下自发活动，由于外在或内在的收缩的胃或内脏的扩张。测量相应纤维的传导速度。食管纤维的测量值分别为2.7-12.8 m/s（平均值：5.7），L.E.S.的测量值分别为1.0-1.3 m/s（平均值：1.1）。胃神经纤维为1.0- 1.7m/s（平均1.3）。食管的是小尺寸的有髓纤维，而其他的是无髓的。
The unitary activity of 60 sensory vagal neurons was recorded from the nodose ganglion of anesthetized young sheep. They originated from the inferior thoracic esophagus (14 receptors), from the lower esophageal sphincter (LES) (16 receptors) and from the stomach (30 receptors). The mechanoreceptors located in the inferior thoracic esophagus were activated both by distension and contraction of the viscera. They belong to the slowly adapting type, except 1 receptor which gave an on-off effect during strong distensions. The mechanoreceptors of the L.E.S. region were quite similar to esophageal slowly adapting endings. They often presented a tonic spontaneous activity which was sometimes modulated by the respiratory rhythm. The gastric receptors were found in the different parts of the stomach: reticulum, rumen, esophageal groove, but they were concentrated in the region including the esophageal groove, the posterior part of the reticulum and the anterior part of the rumen. They adapted slowly to moderate mechanical stimulations (distension and contraction) and they presented in some cases spontaneous activity due to extrinsic or intrinsic contractions of the stomach or to the distension of the viscera. The conduction velocity of the corresponding fibers was measured. The values obtained were respectively of 2.7-12.8 m/s (mean:5.7) for the esophageal fibers, 1.0-1.3 m/s (mean:1.1) for the L.E.S. fibers and 1.0-1.7 m/s (mean:1.3) for the gastric ones. The esophageal ones were small sized myelinated fibers, whereas the others were non-medullated.