A major Y-chromosome haplogroup R1b Holocene era founder effect in Central and Western Europe
A major Y-chromosome haplogroup R1b Holocene era founder effect in Central and Western Europe
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DOI：
10.1038/ejhg.2010.146
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发表时间：
2011-01-01
影响因子：
5.2
通讯作者：
Underhill, Peter A.
中科院分区：
文献类型：
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作者：
Myres, Natalie M.;Rootsi, Siiri;Underhill, Peter A.
核心Y染色体单倍群R-M207内的许多分支的系统发育关系支持单倍群R1 b起源于西亚，其最初的分化在那里，随后其携带M269突变的亚分支之一迅速传播到欧洲。在这里，我们提出了来自118个西亚和欧洲人群的2043个M269衍生Y染色体的地理分辨数据，这些人群评估了M412 SNP，该SNP在很大程度上将大多数中欧和西欧R1 b谱系与东欧，环乌拉尔地区，近东，高加索和巴基斯坦的R1 b谱系分开。在M412的二分法中，主要的S116子分支在多瑙河上游盆地和巴黎地区显示出频率峰值，而向意大利、伊比利亚、法国南部和不列颠群岛的频率下降。虽然这种频率模式非常接近新石器时代文化Linearbandkeramik（LBK）的传播，但这种文化的出现导致了过去一些史前文化的发展，
The phylogenetic relationships of numerous branches within the core Y-chromosome haplogroup R-M207 support a West Asian origin of haplogroup R1b, its initial differentiation there followed by a rapid spread of one of its sub-clades carrying the M269 mutation to Europe. Here, we present phylogeographically resolved data for 2043 M269-derived Y-chromosomes from 118 West Asian and European populations assessed for the M412 SNP that largely separates the majority of Central and West European R1b lineages from those observed in Eastern Europe, the Circum-Uralic region, the Near East, the Caucasus and Pakistan. Within the M412 dichotomy, the major S116 sub-clade shows a frequency peak in the upper Danube basin and Paris area with declining frequency toward Italy, Iberia, Southern France and British Isles. Although this frequency pattern closely approximates the spread of the Linearbandkeramik (LBK), Neolithic culture, an advent leading to a number of pre-historic cultural developments during the past