Organ-on-a-Chip Technologies Network special issue editorial

Organ-on-a-Chip Technologies Network special issue editorial
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芯片器官技术网络特刊社论

DOI:
10.1007/s44164-022-00039-4
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发表时间:
2022
期刊:
In vitro models
影响因子:
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通讯作者:
Biddle A
Biddle A
中科院分区:
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文献类型:
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作者:
Biddle A

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很高兴能特邀编辑这期体外模型特刊,重点介绍英国器官芯片技术网络成员的成就和帮助我们的研讨会系列取得如此成功的主旨演讲者(cpm)。qmul。AC. uk/events/old)。在过去几年主持这些专题讨论会和编辑这一特刊的过程中,出现了一些关键主题。这些主题代表了当前的挑战和机遇,以及器官芯片领域的深入研究领域:1。根据两个不同的目标,该领域的分离:一个是寻求开发比现状更准确的监管测试,并取代动物测试作为监管要求,另一个是寻求开发易于处理的体外模型系统,准确地概括人类生理学和病理生理学方面的发现科学。
It has been a great pleasure to guest edit this special issue of in vitro models that focusses on the achievements of members of the UK Organ-on-a-Chip Technologies Network and the keynote speakers who helped make our symposium series such a success (cpm. qmul. ac. uk/events/old). In chairing these symposia over the last few years and editing this special issue, some key themes have emerged. These themes represent current challenges and opportunities, and areas of intense investigation within the organ-on-a-chip field:1. A separation of the field according to two distinct objectives: one which seeks to develop regulatory tests which can be more accurate than the status quo and replace animal testing as a regulatory requirement, and another which seeks to develop tractable in vitro model systems which accurately recapitulate aspects of human physiology and pathophysiology for discovery science.