Long-term results after laparoscopic sleeve gastrectomy in a large monocentric series
Long-term results after laparoscopic sleeve gastrectomy in a large monocentric series
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DOI：
10.1016/j.soard.2015.09.028
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发表时间：
2016-05-01
影响因子：
3.1
通讯作者：
Basso, Nicola
中科院分区：
文献类型：
--
作者：
Casella, Giovanni;Soricelli, Emanuele;Basso, Nicola
背景资料：腹腔镜袖状胃切除术（SG）作为一种独立的减肥手术已经非常流行，因为在体重减轻和合并症解决方面的短期和中期结局非常积极。然而，长期的结果，从大型series still are sparsely.Objectives：为了评估长期的临床结果，SG在一个大型系列的患者接受SG作为一个独立的procedure.Setting：大学医院在意大利.Methods：前瞻性收集的数据，从182例接受SG在2006年和2008年之间在作者的机构进行回顾性分析。结果：平均初始体重指数（BMI）为45.9 +/- 7.3 kg/m2。8例患者（5.4%）发生严重术后并发症：4例泄漏、2例出血、1例腹腔积液和1例吞咽困难。所有并发症均采用保守治疗。148例患者（81.4%）完成了72个月（6年）随访。37例患者（25%）达到了84个月的随访。在第6年随访时，平均BMI和平均过度体重减轻百分比（%EWL）分别为30.2 kg/m2和67.3%。平均总体重减轻为44.9 kg，而123名患者（83.1%）的%EWL > 50。术前BMI对术后%EWL无显著影响。2型糖尿病、动脉高血压、阻塞性睡眠呼吸暂停综合征和胃食管反流病症状的缓解率分别为83.8%、59.7%、75.6%和64.7%patients.Conclusion：%EWL和合并症的缓解率在SG后持续6年和7年。术前BMI不能预测体重减轻的结果。(C)2016年美国代谢和减肥外科学会。All rights reserved.
Background: Laparoscopic sleeve gastrectomy (SG) has gained great popularity as a stand-alone bariatric procedure because short- and mid-term outcomes in terms of weight loss and resolution of co-morbidities have been very positive. However, long-term results from large series still are sparse.Objectives: To evaluate the long-term clinical outcomes of SG in a large series of patients undergoing SG as a stand-alone procedure.Setting: University hospital in Italy.Methods: A retrospective analysis of prospectively collected data from 182 patients undergoing SG between 2006 and 2008 in the authors' institution. Long-term outcomes at 6 and 7 years were analyzed in terms of weight loss and co-morbidities resolution.Results: Mean initial body mass index (BMI) was 45.9 +/- 7.3 kg/m(2). Major postoperative complications occurred in 8 patients (5.4%): 4 leaks, 2 bleeding, 1 abdominal collection, and 1 dysphagia. All complications were managed conservatively. One hundred forty-eight patients (81.4%) completed the 72-month (6-year) follow-up. Thirty-seven patients (25%) reached a follow-up of 84 months. At year 6 follow-up the mean BMI and the mean percentage of excess weight loss (%EWL) were 30.2 kg/m(2) and 67.3%, respectively. Mean total body weight loss was 44.9 kg, while a %EWL > 50 was registered in 123 patients (83.1%). Preoperative BMI did not significantly influence postoperative %EWL. Remission of type 2 diabetes mellitus, arterial hypertension, obstructive sleep apnea syndrome, and gastroesophageal reflux disease symptoms occurred in 83.8%, 59.7%, 75.6%, and 64.7% of patients, respectively.Conclusion: %EWL and resolution of co-morbidities appear to be sustained 6 and 7 years after SG. Preoperative BMI is not predictive for weight loss outcomes. (C) 2016 American Society for Metabolic and Bariatric Surgery. All rights reserved.