Assessment of fetal lung growth in utero with echo-planar MR imaging
Assessment of fetal lung growth in utero with echo-planar MR imaging
复制标题
DOI：
10.1148/radiology.210.1.r99ja42197
复制
发表时间：
1999-01-01
期刊：
影响因子：
19.7
通讯作者：
Johnson, IR
中科院分区：
文献类型：
--
作者：
Duncan, KR;Gowland, PA;Johnson, IR
目的：应用平面回波磁共振成像技术测量正常胎儿肺体积随孕龄增加的变化。材料与方法：对56例19周至足月的单胎胎儿进行肺体积纵向测量。结果：肺体积随孕8~125mL呈指数增长。体积与孕周的关系式为：体积=0.8375e(0.1249g)(R-2=0.77)，其中g=孕周。随着孕龄增加，肺体积与胎儿体积呈正相关(R2=0.75)。羊水量与肺容量之间无显著相关性(R2=0.11)。结论：无论羊水量的变化如何，均可用平面回波磁共振成像来评估肺容量的变化。这些测量值低于尸检和新生儿研究的测量值，但与使用三维超声获得的测量值相似。当需要对肺体积进行非侵入性评估时，使用回声平面成像获得的肺体积估计可能具有重要的临床和研究应用。
PURPOSE: To measure changes in normal fetal lung volume with increasing gestation by using echo-planar magnetic resonance (MR) imaging.MATERIALS AND METHODS: Fifty-six singleton fetuses were examined longitudinally with respect to lung volume by using echo-planar MR imaging between 19 weeks gestation and term.RESULTS: Lung volume increased exponentially with gestation from 8 to 125 mL. Volume was related to gestation by using the equation, volume = 0.8375e(0.1249g) (R-2 = 0.77), where g = gestation. Lung volume had a direct relationship to fetal volume with increasing gestation (R-2 = 0.75). There was no significant relationship between amniotic fluid volume and lung volume (R-2 = 0.11).CONCLUSION: Variation in lung volumes can be assessed by using echo-planar MR imaging, regardless of variations in amniotic fluid volume. These measurements are less than those obtained from postmortem and neonatal studies but are similar to those obtained by using three-dimensional ultrasonography. Lung volume estimations obtained by using echo-planar imaging may have important clinical and research applications when noninvasive assessment of lung volume is required.