Effects of chlorhexidine (gel) application on bacterial levels and orthodontic brackets during orthodontic treatment
Effects of chlorhexidine (gel) application on bacterial levels and orthodontic brackets during orthodontic treatment
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DOI：
10.2334/josnusd.58.35
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发表时间：
2016-03-01
影响因子：
1.9
通讯作者：
Hassan, Ali H.
中科院分区：
文献类型：
--
作者：
Al-Bazi, Samar M.;Abbassy, Mona A.;Hassan, Ali H.
本研究的目的是评价0.50%洗必泰（CHX）凝胶应用口腔给药系统（3DS）对唾液变形链球菌（S。变形菌）以及金属和陶瓷正畸托槽的表面形貌。该研究涉及20名患有高水平唾液S的正畸患者。变异体患者接受专业机械牙齿清洁，然后使用个体托盘（3DS）应用0.50% CHX。Salivary S.在治疗后1、2、4和8周重复测量变形蛋白水平。在体外研究中，使用40个陶瓷和金属托槽浸泡在0.50%CHX凝胶中10分钟，而另一个未处理的40个托槽作为对照。使用万能试验机记录CHX处理前后不锈钢丝与托槽的摩擦阻力。扫描电子显微镜用于比较托槽表面形貌的变化。使用统计分析来确定CHX对细菌计数的影响，并评估CHX对摩擦阻力的影响。根据本研究结果，S。变形杆菌水平显著降低（P < 0.05）。使用CHX前后，托槽的摩擦阻力和表面形貌无明显变化。
The objectives of this study were to evaluate the effects of applying 0.50% chlorhexidine (CHX) gel using the dental drug delivery system (3DS) on salivary Streptococcus mutans (S. mutans) and on the surface topography of metal and ceramic orthodontic brackets. The study involved 20 orthodontic patients with high levels of salivary S. mutans. The patients were treated with professional mechanical tooth cleaning followed by application of 0.50% CHX using individual trays (3DS). Salivary S. mutans levels were repeatedly measured 1, 2, 4, and 8 weeks post-treatment. In vitro study utilized forty ceramic and metallic brackets that were immersed in 0.50% CHX gel for 10 min, whereas another untreated forty brackets served as controls. The frictional resistances of stainless steel wires to the brackets before and after CHX treatment were recorded using a universal testing machine. Scanning electron microscopy was used to compare changes in the surface topography of brackets. Statistical analyses were used to determine the effect of CHX on bacterial count and to evaluate the effect of CHX on frictional resistance. According to the results of this study, S. mutans levels were reduced significantly (P < 0.05). There were no significant changes in the frictional resistance and surface topography of brackets before or after application of CHX.