Risk factors for urinary tract infection in children: A population-based study of 2856 children
Risk factors for urinary tract infection in children: A population-based study of 2856 children
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DOI：
10.1111/j.1440-1754.2008.01435.x
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发表时间：
2009-03-01
影响因子：
1.7
通讯作者：
Craig, Jonathan C.
中科院分区：
文献类型：
--
作者：
Sureshkumar, Premala;Jones, Mike;Craig, Jonathan C.
目的：为了确定儿童尿路感染（UTI）的危险因素，告知预防Strategy.Method的发展：一个有效的问卷调查，包括人口统计学因素，围产期，发育，肠道和泌尿系统的历史被发送到一个横截面样本的小学生的父母随机选择的前4年的学校。UTI确定由父母的报告，验证了交叉引用与微生物报告的所有阳性病例和50个随机选择的阴性cases.Results：2856名儿童（平均年龄7.3岁，范围4.8-12.8岁）的父母作出回应。共有3.6%的儿童有细菌学证实的UTI，而仅通过父母报告的比例为12.6%。多变量多分类logistic回归分析显示，结构性肾脏异常（OR 15.7，95%置信区间8.1-30.4）、日间尿失禁（OR 2.6，1.6-4.5）、女性（OR 2.4，1.5-3.8）和大便失禁（OR 1.9，1.1-3.4）病史与UTI独立相关。日间尿失禁增加的风险在男孩（8.3%比1.2%）比女孩（8.1%比4.6%），和肾脏问题增加的风险在年龄较大的孩子比年幼的孩子（29%比2%在>= 8奥尔兹，0%比4%在4-6奥尔兹）。有效治疗日间尿失禁和大便失禁可以预防儿童，特别是男孩的UTI。
Aim: To identify risk factors for urinary tract infection (UTI) in children to inform the development of preventative strategies.Method: A validated questionnaire covering demographic factors, perinatal, developmental, bowel and urinary history was sent to a cross-sectional sample of parents of elementary school children randomly selected from the first 4 years of school. UTI was ascertained by parental report, verified by cross-referencing with microbiological reports for all positive cases and 50 randomly selected negative cases.Results: Parents of 2856 children (mean age 7.3 years, range 4.8-12.8 years) responded. A total of 3.6% of children had a bacteriologically verified UTI, compared with 12.6% by parental report alone. Multivariate polychotomous logistic regression showed that a history of structural kidney abnormalities (odds ratio (OR) 15.7, 95% confidence interval 8.1-30.4), daytime incontinence (OR 2.6, 1.6-4.5), female gender (OR 2.4, 1.5-3.8), and encopresis (OR 1.9, 1.1-3.4) were independently associated with UTI. Daytime incontinence increased risk more in boys (8.3% vs. 1.2%) than girls (8.1% vs. 4.6%), and kidney problems increased risk in older compared with younger children (29% vs. 2% in >= 8 year olds, 0% vs. 4% in 4-6 year olds).Conclusions: Parents over-report UTI by about threefold. Effective treatment of daytime urinary incontinence and encopresis may prevent UTI in children, especially boys.