HIV Pre-exposure Prophylaxis (PrEP) Uptake and Retention Among Men Who Have Sex with Men in a Community-Based Sexual Health Clinic.

HIV Pre-exposure Prophylaxis (PrEP) Uptake and Retention Among Men Who Have Sex with Men in a Community-Based Sexual Health Clinic.
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DOI:
10.1007/s10461-017-2009-x
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发表时间:
2018-04
期刊:
影响因子:
4.4
通讯作者:
Carrico A
Carrico A
中科院分区:
医学2区
文献类型:
--
作者:
Hojilla JC;Vlahov D;Crouch PC;Dawson-Rose C;Freeborn K;Carrico A

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在加州旧金山弗朗西斯科的一家为男男性行为者(MSM)提供服务的社区诊所中,本研究描述了PrEP级联的关键步骤,并确定了保持护理的相关性。总共有344名患者接受了PrEP评估。四分之三(78%)寻求PrEP服务的患者开始了PrEP。13个月时停止PrEP的总体累积发生率为38%。患有性传播感染(STI)的男性被保留的可能性降低了44%(调整后的风险比[aHR] 0.56,95%置信区间[0.33 - 0.95])。对患有性传播感染的男性进行全面的保留工作对于优化PrEP的益处至关重要。
In a community-based clinic serving men who have sex with men (MSM) in San Francisco, California, this study characterized key steps of the PrEP cascade and identified correlates of retention in care. In total, 344 patients were evaluated for PrEP. Three-fourths (78%) of those who sought PrEP services initiated PrEP. The overall cumulative incidence of discontinuing PrEP at 13 months was 38%. Men with a sexually transmitted infection (STI) were 44% less likely to be retained (adjusted hazard ratio [aHR] 0.56, 95% confidence interval [0.33–0.95]). Comprehensive retention efforts for men with STIs are crucial to optimize the benefits of PrEP.
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