Synchronization of oscillatory responses in visual cortex correlates with perception in interocular rivalry
Synchronization of oscillatory responses in visual cortex correlates with perception in interocular rivalry
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DOI：
10.1073/pnas.94.23.12699
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发表时间：
1997-11-11
影响因子：
11.1
通讯作者：
Singer, W
中科院分区：
文献类型：
--
作者：
Fries, P;Roelfsema, PR;Singer, W
在患有早发性斜视的受试者中，双眼传达的信号不是同时感知的，而是交替感知的。我们利用这种眼间抑制的现象，研究了清醒斜视猫初级视皮层中双眼竞争的神经元相关性。单眼呈现的刺激，很容易被动物感知诱发同步放电的振荡模式在γ频率范围内，在双视刺激，神经元响应的刺激，继续被认为增加了同步性和规律性的振荡模式，而相反的是真实的神经元响应的刺激，不再被认为是。这些差异的变化与放电率的变化无关，这表明在视觉处理的早期阶段，同步性的程度，而不是反应的幅度决定了哪些信号被感知和控制行为反应。
In subjects suffering from early onset strabismus, signals conveyed by the two eyes are not perceived simultaneously but in alternation. We exploited this phenomenon of interocular suppression to investigate the neuronal correlate of binocular rivalry in primary visual cortex of awake strabismic cats. Monocularly presented stimuli that were readily perceived by the animal evoked synchronized discharges with an oscillatory patterning in the gamma-frequency range, Upon dichoptic stimulation, neurons responding to the stimulus that continued to be perceived increased the synchronicity and the regularity of their oscillatory patterning while the reverse was true for neurons responding to the stimulus that was no longer perceived. These differential changes were not associated with modifications of discharge rate, suggesting that at early stages of visual processing the degree of synchronicity rather than the amplitude of responses determines which signals are perceived and control behavioral responses.