Clinical and Epidemiological Features of Obstructive Sleep Apnea in a Survey of Down Syndrome Subjects in Japan.
Clinical and Epidemiological Features of Obstructive Sleep Apnea in a Survey of Down Syndrome Subjects in Japan.
复制标题
日本唐氏综合症受试者调查中阻塞性睡眠呼吸暂停的临床和流行病学特征。
DOI：
10.1111/nhs.12206
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发表时间：
2015
影响因子：
2.7
通讯作者：
Ando S.
中科院分区：
文献类型：
--
作者：
Ono J;Chishaki A;Ohkusa T;Sawatari H;Nishizaka M;Ando S.
这项研究评估了日本唐氏综合症患者中阻塞性睡眠呼吸暂停相关症状的患病率，并评估了其与肥胖或异常睡眠姿势的关系。我们获得了90人的人口学特征、睡眠姿势和阻塞性睡眠呼吸暂停相关症状，这是他们的照顾者报告的。尽管71%的人报告打鼾声，59%的人报告有觉醒，但肥胖者和非肥胖者的阻塞性睡眠呼吸暂停相关症状没有显著差异。最年轻的年龄组有最少的阻塞性睡眠呼吸暂停相关症状，特别是鼾症。在不寻常的睡眠姿势组中，觉醒、夜尿和呼吸暂停的几率往往更高。不寻常的睡眠姿势在6-15岁年龄组中最常见。患有唐氏综合症的人可能会以不寻常的姿势睡觉，以避免其他解剖因素造成的上呼吸道阻塞。对于在主流服务中工作的护士和其他卫生专业人员来说，重要的是对所有唐氏综合症患者进行阻塞性睡眠呼吸暂停症状的筛查，特别是6岁及以上的患者，并转介他们进行睡眠障碍的进一步评估。
This study evaluated the prevalence of obstructive sleep apnea‐related symptoms and assessed the relationship with obesity or unusual sleep postures in Down syndrome patients in Japan. We obtained the demographic characteristics, sleep postures, and obstructive sleep apnea‐related symptoms experienced by 90 people as reported by their caregivers. Although 71% reported snoring and 59% arousals, obstructive sleep apnea‐related symptoms were not significantly different between obese and non‐obese participants. The youngest age group had the fewest obstructive sleep apnea‐related symptoms, especially symptoms of snoring. The odds for arousal, nocturia, and apnea tended to be higher in the unusual sleep‐postures group. Unusual sleep postures were most frequent in the group 6–15 years of age. People with Down syndrome might sleep in unusual postures to avoid upper airway obstruction caused by other anatomical factors. For nurses and other health professionals working in mainstream service, it is important to screen all persons with Down syndrome for symptoms suggestive of obstructive sleep apnea, particularly those six years of age and older, and to refer them for further evaluation for sleep disorders.