An organic dye with very large Stokes-shift and broad tunability of fluorescence: Potential two-photon probe for bioimaging and ultra-sensitive solid-state gas sensor
An organic dye with very large Stokes-shift and broad tunability of fluorescence: Potential two-photon probe for bioimaging and ultra-sensitive solid-state gas sensor
复制标题
具有非常大的斯托克斯位移和广泛的荧光可调性的有机染料：用于生物成像和超灵敏固态气体传感器的潜在双光子探针
DOI：
10.1063/1.4939232
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发表时间：
2016-01-04
影响因子：
4
通讯作者：
Sun, Handong
中科院分区：
文献类型：
--
作者：
He, Tingchao;Wang, Yue;Sun, Handong
发光的非线性光学分子，特别是那些具有大的斯托克斯位移和宽的可调谐性，其发射波长，引起了相当大的关注，在各种应用，包括生物医学成像和荧光传感器。然而，由于斯托克斯位移小、荧光发射的可调性窄以及高极性溶剂中的光学非线性小，大多数荧光发色团在此类应用中的潜力有限。在这项工作中，我们证明了双光子吸收二苯乙烯发色团在二甲基亚砜（DMSO）中表现出大的双光子吸收作用截面（ηδ = 320 GM），并通过操纵周围介质的极性显示出宽的荧光调谐性（125 nm）。重要的是，在DMSO中实现了高达227 nm的非常大的斯托克斯位移。由于这些特性，这种发色团可以用作生物成像应用的双光子探针和超灵敏固态气体检测器。
Light-emitting nonlinear optical molecules, especially those with large Stokes shifts and broad tunability of their emission wavelength, have attracted considerable attention for various applications including biomedical imaging and fluorescent sensors. However, most fluorescent chromophores have only limited potential for such applications due to small Stokes shifts, narrow tunability of fluorescence emissions, and small optical nonlinearity in highly polar solvents. In this work, we demonstrate that a two-photon absorbing stilbene chromophore exhibits a large two-photon absorption action cross-section (ηδ = 320 GM) in dimethylsulfoxide (DMSO) and shows broad fluorescence tunability (125 nm) by manipulating the polarity of the surrounding medium. Importantly, a very large Stokes shift of up to 227 nm is achieved in DMSO. Thanks to these features, this chromophore can be utilized as a two-photon probe for bioimaging applications and in an ultrasensitive solid-state gas detector.