Uveal melanoma: From diagnosis to treatment and the science in between.
Uveal melanoma: From diagnosis to treatment and the science in between.
复制标题
卵子黑色素瘤:从诊断到治疗以及两者之间的科学。
DOI:
10.1002/cncr.29727
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发表时间:
2016-08-01
期刊:
影响因子:
6.2
通讯作者:
Patel SP
中科院分区:
文献类型:
--
作者:
Chattopadhyay C;Kim DW;Gombos DS;Oba J;Qin Y;Williams MD;Esmaeli B;Grimm EA;Wargo JA;Woodman SE;Patel SP
Melanomas of the choroid, ciliary body, and iris of the eye are collectively known as uveal melanomas. These cancers represent 5% of all melanoma diagnoses in the U.S., an age-adjusted risk of 5 per million. These less frequent melanomas are dissimilar to their more common cutaneous melanoma relative, with differing risk factors, primary treatment, anatomical spread, molecular changes, and responses to systemic therapy. Once metastatic, therapy options are limited, and often extrapolated from cutaneous melanoma therapies despite routine exclusion of uveal melanoma from clinical trials. Clinical trials directed at uveal melanoma have been completed or are in progress and data from these well-designed investigations will help guide future directions in this orphan disease.
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DOI:
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发表时间:
2011-07
期刊:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
影响因子:
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