Protein variation in blood-dwelling schistosome worms generated by differential splicing of micro-exon gene transcripts
Protein variation in blood-dwelling schistosome worms generated by differential splicing of micro-exon gene transcripts
复制标题
DOI：
10.1101/gr.100099.109
复制
发表时间：
2010-08-01
期刊：
影响因子：
7
通讯作者：
Wilson, R. Alan
中科院分区：
文献类型：
--
作者：
DeMarco, Ricardo;Mathieson, William;Wilson, R. Alan
曼氏血吸虫是一种适应良好的血液寄生蠕虫，尽管不断暴露于潜在的免疫攻击，但仍能在人类宿主体内存活数十年。在这里，我们详细描述了mansoni的微外显子基因（MEG），其中一些存在于多个拷贝中，它们代表了一种新的分子系统，通过短(
Schistosoma mansoni is a well-adapted blood-dwelling parasitic helminth, persisting for decades in its human host despite being continually exposed to potential immune attack. Here, we describe in detail micro-exon genes (MEG) in S. mansoni, some present in multiple copies, which represent a novel molecular system for creating protein variation through the alternate splicing of short (