Association between childhood socioeconomic status and subjective memory complaints among older adults: results from the Japan Gerontological Evaluation Study 2010
Association between childhood socioeconomic status and subjective memory complaints among older adults: results from the Japan Gerontological Evaluation Study 2010
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DOI：
10.1017/s1041610219000814
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发表时间：
2019-12-01
影响因子：
7
通讯作者：
Kondo, Katsunori
中科院分区：
文献类型：
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作者：
Nishizawa, Toshinori;Morita, Ayako;Kondo, Katsunori
背景：主观记忆主诉(SMC)被认为是轻度认知损害和痴呆的早期标志。然而，关于早期生活条件对老年SMC发育的影响的证据很少。这项研究旨在调查社区老年人童年社会经济地位(SES)和SMC之间的关系。方法：我们使用了日本老年评估研究的数据，这是一项基于人群的队列研究，研究对象是来自日本28个城市的65岁或65岁以上的老年人。从2010年实施的自我报告问卷(n=16,184)中评估儿童的SES和日常生活中的SMC。泊松回归被用来确定它们之间的关联，调整了潜在的混杂因素和生活过程中介因素，并检查了队列效应。结果：我们在47.4%的参与者中发现了SMC。在调整了性别、年龄和兄弟姐妹的数量后，与儿童时期的高SES相比，儿童低和中等SES分别与SMC的患病率(患病率[PR]：1.29，95%可信区间：1.22，1.36)和10%的SMC患病率(PR：1.10，95%CI：1.04，1.17)相关(p
Background: Subjective memory complaints (SMC) have been suggested as an early marker of mild cognitive impairment and dementia. However, there is a paucity of evidence on the effects of early life conditions on the development of SMC in old age. This study is aimed at investigating the association between childhood socioeconomic status (SES) and SMC in community-dwelling older adults. Methods: We used the data of the Japan Gerontological Evaluation Study, a population-based cohort study of people aged 65 years or older enrolled from 28 municipalities across Japan. Childhood SES and SMC in everyday life were assessed from the self-report questionnaire administered in 2010 (n = 16,184). Poisson regression was performed to determine their association, adjusted for potential confounders and life-course mediators and examined cohort effects. Results: We identified SMC in 47.4% of the participants. After adjusting for sex, age, and number of siblings, low and middle childhood SES were associated with 29% (prevalence ratio [PR]: 1.29, 95% confidence interval [CI]: 1.22, 1.36) and 10% higher prevalence of SMC (PR: 1.10, 95%CI: 1.04, 1.17), respectively, compared with high childhood SES (p for trend