Comparing Moral Judgments of Patients With Frontotemporal Dementia and Frontal Stroke
Comparing Moral Judgments of Patients With Frontotemporal Dementia and Frontal Stroke
复制标题
DOI：
10.1001/jamaneurol.2014.347
复制
发表时间：
2014-09-01
期刊：
影响因子：
29
通讯作者：
Ibanez, Agustin
中科院分区：
文献类型：
--
作者：
Baez, Sandra;Couto, Blas;Ibanez, Agustin
重要性一些临床报告指出，前额叶病变或额颞叶痴呆的行为变异患者共享社会认知障碍。道德推理受损，在这两种情况下，但一直很少有调查，直接比较这一领域的2 groups.OBSERVATIONS这项工作比较了这些患者群体的道德判断，使用一项任务，旨在解开的意图和结果的贡献，在道德判断。对于这两种疾病，患者判断的情况下，主角认为他们会造成伤害，但没有比对照组更允许。此外，额颞叶痴呆症患者在没有有害意图的情况下判断有害结果比对照参与者更不允许。有2 conditions.Conclusions和相关性之间没有差异这两种疾病涉及的障碍，在整合意图和结果信息的道德判断。据我们所知，这项研究是第一次直接比较两种不同病因的额叶病变的社会认知领域。我们的研究结果强调了比较血管病变患者和神经退行性疾病患者的重要性。
IMPORTANCE Several clinical reports have stated that patients with prefrontal lesions or patients with the behavioral variant of frontotemporal dementia share social cognition impairments. Moral reasoning is impaired in both conditions but there have been few investigations that directly compare this domain in the 2 groups.OBSERVATIONS This work compared the moral judgments of these patient groups using a task designed to disentangle the contributions of intentions and outcomes in moral judgment. For both disorders, patients judged scenarios where the protagonists believed that they would cause harm but did not as being more permissible than the control group. Moreover, patients with frontotemporal dementia judged harmful outcomes in the absence of harmful intentions as less permissible than the control participants. There were no differences between the 2 conditions.CONCLUSIONS AND RELEVANCE Both disorders involved impairments in integrating intention and outcome information for moral judgment. This study was the first, to our knowledge, to directly compare a social cognition domain in 2 frontal pathologies with different etiology. Our results highlighted the importance of comparing patients with vascular lesions and patients with neurodegenerative diseases.