Dynamics of a semiflexible polar filament in Stokes flow.
Dynamics of a semiflexible polar filament in Stokes flow.
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斯托克斯流中半柔性极性细丝的动力学。
DOI：
10.1103/physreve.82.016309
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
Y. Young
中科院分区：
文献类型：
--
作者：
Y. Young
在这项工作中，动力学和运输的极性驱动的灯丝检查使用连续体细长体模型。浸没在粘性流体中，细丝从马达蛋白（锚定在运动测定上）获得极性推进，同时经历来自底壁的粘性阻力。直线极丝的线性分析结果说明了空间不均匀性对屈曲不稳定性的必要性。在数值模拟中，随后的屈曲导致细丝变形、波动和其运动方向的改变。在两种类型的马达蛋白浓度景观中重复的细丝屈曲导致极性细丝在尺度上的扩散运输远大于平均自由路径和细丝屈曲事件之间的平均持续时间。
In this work, the dynamics and transport of a polarly driven filament is examined using a continuum slender-body model. Immersed in a viscous fluid, the filament gains polar propulsion from the motor proteins (anchored on the motility assay) while experiencing a viscous drag from the bottom wall. Results from the linear analysis on a straight polar filament illustrate the necessity of spatial inhomogeneity in the polar forcing for the buckling instability. The ensuing buckling leads to filament deformation, undulation, and change of its direction of motion in the numerical simulations. Repeated filament buckling in two types of motor protein concentration landscape results in diffusive transport of a polar filament on scales much larger than the mean-free path and the average duration between filament buckling events.