A Likely Ancient Genome Duplication in the Speciose Reef-Building Coral Genus, Acropora
A Likely Ancient Genome Duplication in the Speciose Reef-Building Coral Genus, Acropora
复制标题
DOI：
10.1016/j.isci.2019.02.001
复制
发表时间：
2019-02
期刊：
影响因子：
5.8
通讯作者：
Yafei Mao;N. Satoh
中科院分区：
文献类型：
--
作者：
Yafei Mao;N. Satoh
全基因组复制（Whole-genome duplication，WGD）被认为是多种生物起源和多样性的重要进化力量，而珊瑚礁中的鹿角珊瑚（Acropora）被认为是由多倍性起源的。然而，没有遗传学证据支持这一假设。利用综合的基因组学和比较基因组学方法，我们分析了六个鹿角珊瑚的基因组，发现一个WGD事件可能发生在2.31亿年前，在最近的共同祖先鹿角珊瑚，同时在世界范围内的珊瑚灭绝。我们发现，重复的基因高度富集的基因调控功能，包括应激反应。重复基因的功能簇与发育过程中基因表达模式的分化有关。顶孔虫与其他刺胞动物的WGD产生了一些蛋白质类毒素。总的来说，这项研究提供了证据，一个古老的WGD事件的珊瑚，这有助于解释的起源和多样化的鹿角珊瑚。
Whole-genome duplication (WGD) has been recognized as a significant evolutionary force in the origin and diversification of multiple organisms.Acropora, a speciose reef-building coral genus, is suspected to have originated by polyploidy. Yet, there is no genetic evidence to support this hypothesis. Using comprehensive phylogenomic and comparative genomic approaches, we analyzed sixAcroporidgenomes and found that a WGD event likely occurred ∼31 million years ago in the most recent common ancestor ofAcropora, concurrent with a worldwide coral extinction. We found that duplicated genes were highly enriched in gene regulation functions, including those of stress responses. The functional clusters of duplicated genes are related to the divergence of gene expression patterns during development. Some proteinaceous toxins were generated by WGD inAcroporacompared with other cnidarian species. Collectively, this study provides evidence for an ancient WGD event in corals, which helps explain the origin and diversification ofAcropora.