Household-based HIV counseling and testing as a platform for referral to HIV care and medical male circumcision in Uganda: a pilot evaluation.
Household-based HIV counseling and testing as a platform for referral to HIV care and medical male circumcision in Uganda: a pilot evaluation.
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DOI：
10.1371/journal.pone.0051620
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发表时间：
2012
期刊：
影响因子：
3.7
通讯作者：
Celum C
中科院分区：
文献类型：
--
作者：
Tumwebaze H;Tumwesigye E;Baeten JM;Kurth AE;Revall J;Murnane PM;Chang LW;Celum C
艾滋病毒综合预防举措包括适合特定人群并可接受的循证、生物医学和行为干预措施，旨在大幅降低人口一级的艾滋病毒发病率。了解艾滋病毒血清状况是与艾滋病毒护理和预防相联系的关键。以家庭为基础的艾滋病毒咨询和检测（HBCT）可以实现高艾滋病毒检测率。我们评估了HBCT作为在撒哈拉以南非洲提供艾滋病毒预防综合服务的平台。我们在乌干达西南部的一个半城市地区进行了HBCT。所有成年人都收到了标准的艾滋病毒预防信息。实时电子数据收集包括一个简短的风险评估和预防分流算法，用于将艾滋病毒血清反应阳性者转诊到艾滋病毒护理和将有多个性伴侣的未割包皮的艾滋病毒血清反应阴性男子转诊到男性包皮环切术。每月进行3个月的跟踪访问，以促进艾滋病毒护理和男性包皮环切术的接受。855个家庭接受了HBCT; 1 941名成年人中有1 587名（81.8%）参加了HBCT访问，1 557名（98.1%）接受了检测并获得了艾滋病毒结果，其中46.5%为男性。共有152例（9.8%）为HIV血清阳性，其中位CD 4计数为456个细胞/µL，50.7%为新确定的HIV血清阳性。HBCT后三个月，88.5%的HIV血清阳性者曾前往HIV护理诊所;在CD 4计数<250个细胞/微升的患者中，71.4%开始接受抗逆转录病毒治疗。在123名艾滋病毒血清阴性男性中，有一名艾滋病毒阳性伴侣或多名伴侣，62.0%的人在第3个月接受了包皮环切术。HBCT实现了对艾滋病毒血清状况的高度了解，是一个有效的平台，可用于查明高危人群，并通过转诊和有针对性的后续行动，实现比通过其他单一重点战略更高的艾滋病毒预防和护理服务利用率。
Combination HIV prevention initiatives incorporate evidence-based, biomedical and behavioral interventions appropriate and acceptable to specific populations, aiming to significantly reduce population-level HIV incidence. Knowledge of HIV serostatus is key to linkages to HIV care and prevention. Household-based HIV counseling and testing (HBCT) can achieve high HIV testing rates. We evaluated HBCT as a platform for delivery of combination HIV prevention services in sub-Saharan Africa. We conducted HBCT in a semi-urban area in southwestern Uganda. All adults received standard HIV prevention messaging. Real-time electronic data collection included a brief risk assessment and prevention triage algorithm for referrals of HIV seropositive persons to HIV care and uncircumcised HIV seronegative men with multiple sex partners to male circumcision. Monthly follow-up visits for 3 months were conducted to promote uptake of HIV care and male circumcision. 855 households received HBCT; 1587 of 1941 (81.8%) adults were present at the HBCT visit, 1557 (98.1% of those present) were tested and received HIV results, of whom, 46.5% were men. A total of 152 (9.8%) were HIV seropositive, for whom the median CD4 count was 456 cells/µL, and 50.7% were newly-identified as HIV seropositive. Three months after HBCT, 88.5% of HIV seropositive persons had attended an HIV care clinic; among those with CD4 counts <250 cells/µL, 71.4% initiated antiretroviral therapy. Among 123 HIV seronegative men with an HIV+ partner or multiple partners, 62.0% were circumcised by month 3. HBCT achieves high levels of knowledge of HIV serostatus and is an effective platform for identifying at-risk persons and achieving higher uptake of HIV prevention and care services through referrals and targeted follow-up than has been accomplished through other single focus strategies.
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影响因子：
6
作者：
Nuwaha, Fred;Kasasa, Simon;Tumwesigye, Elioda
通讯作者：
Tumwesigye, Elioda
影响因子：
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作者：
Tumwesigye, Elioda;Wana, Goodwill;Nuwaha, Fred
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Nuwaha, Fred
影响因子：
11.8
作者：
Wachira, Juddy;Kimaiyo, Sylvester;Braitstein, Paula
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Braitstein, Paula
影响因子：
168.9
作者：
May, Margaret;Boulle, Andrew;Phiri, Sam;Messou, Eugene;Myer, Landon;Wood, Robin;Keiser, Olivia;Sterne, Jonathan A. C.;Dabis, Francois;Egger, Matthias
通讯作者：
Egger, Matthias
在乌干达的城市社区环境中，高度接受家庭艾滋病毒咨询和测试。
影响因子：
4.5
作者：
Sekandi JN;Sempeera H;List J;Mugerwa MA;Asiimwe S;Yin X;Whalen CC
通讯作者：
Whalen CC