Mycoplasma pneumoniae infection-induced erythema nodosum, anaphylactoid purpura, and acute urticaria in 3 people in a single family
Mycoplasma pneumoniae infection-induced erythema nodosum, anaphylactoid purpura, and acute urticaria in 3 people in a single family
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DOI：
10.1016/j.jaad.2005.08.027
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发表时间：
2007-08-01
影响因子：
13.8
通讯作者：
Shiohara, Tetsuo
中科院分区：
文献类型：
--
作者：
Kano, Yoko;Mitsuyama, Yoko;Shiohara, Tetsuo
肺炎支原体感染是呼吸道疾病最常见的病原体之一。虽然这种感染的呼吸道症状通常是轻微的，但它往往伴有各种肺外并发症，包括关节炎和皮肤表现。我们报告3例肺炎支原体感染在一个家庭谁透露结节性红斑，过敏性紫癜，急性荨麻疹，分别。我们讨论了这种感染引起的皮肤表现和病毒感染引起的皮肤表现之间的相似性，以及在具有共同遗传背景的人群中由单一感染因子产生不同皮肤病变的负责因素。肺炎支原体感染的皮肤表现中与支原体相关的变异可归因于宿主的适应性免疫的不成熟，如在病毒感染中所提出的。
Mycoplasma pneumoniae infection is one of the most common etiologic agents of respiratory tract diseases. Although the respiratory symptoms of this infection commonly are mild, it often is accompanied by various extrapulmonary complications including arthritis and cutaneous manifestations. We report 3 patients with M pneumoniae infection in a single family who revealed erythema nodosum, anaphylactoid purpura, and acute urticaria, respectively. We discuss the similarity between these cutaneous manifestations caused by this infection and those caused by viral infections, and the responsible factors for producing different cutaneous lesions by a single infectious agent in people with common genetic background. Age-related variations in cutaneous manifestations of M pneumoniae infections can be attributed to the immaturity of the adaptive immunity of a host, as has been suggested in viral infections.