RNA EDITING OF SORGHUM MITOCHONDRIAL ATP6 TRANSCRIPTS CHANGES 15 AMINO-ACIDS AND GENERATES A CARBOXY-TERMINUS IDENTICAL TO YEAST
RNA EDITING OF SORGHUM MITOCHONDRIAL ATP6 TRANSCRIPTS CHANGES 15 AMINO-ACIDS AND GENERATES A CARBOXY-TERMINUS IDENTICAL TO YEAST
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DOI：
10.1007/bf00317071
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发表时间：
1991-01-01
期刊：
影响因子：
2.5
通讯作者：
TANG, HV
中科院分区：
文献类型：
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作者：
KEMPKEN, F;MULLEN, JA;TANG, HV
高粱线粒体atp 6 cDNA克隆的测序揭示了756 bp保守核心基因内的19个C到U转录编辑事件; 3个是沉默的，16个导致15个氨基酸的变化。只有一个编辑，这是沉默的，被发现在381 bp的氨基延伸的核心基因。与酵母atp 6相比，15个变化的氨基酸中有11个与酵母atp 6相同或代表保守变化。将CAA密码子编辑为TAA将羧基末端截短到与酵母相同的位置。在改变氨基酸的位点处的编辑频率非常高，与在沉默的第三碱基位点处的部分编辑相反。
Sequencing of sorghum mitochondrial atp6 cDNA clones revealed 19 C-to-U transcript editing events within a 756 bp-conserved core gene; three were silent and 16 resulted in 15 amino acid changes. Only one edit, which was silent, was found in the 381 bp amino-extension to the core gene. Eleven of the 15 changed amino acids were identical with or else represented conservative changes compared to yeast atp6. Editing of a CAA codon to TAA truncates the carboxy-terminus to a position identical to that of yeast. The frequency of editing at sites which change amino acids was very high in contrast to partial editing at silent, third base, sites.