What is the pain of interstitial cystitis like?
What is the pain of interstitial cystitis like?
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DOI：
10.1007/s00192-005-1344-z
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发表时间：
2006-01-01
影响因子：
1.8
通讯作者：
Propert, K
中科院分区：
文献类型：
--
作者：
FitzGerald, MP;Brensinger, C;Propert, K
为了描述间质性膀胱炎（IC）患者经历的疼痛特征（疼痛部位、严重程度和特征），我们对IC数据库（ICDB）的数据进行了二次分析，这是一项前瞻性、纵向、队列研究IC患者。我们分析了629例患者的横断面基线数据，这些患者有完整的基线症状问卷。患者回答有关过去4周内是否有与泌尿系统症状相关的疼痛或不适的问题，如果有，则回答有关疼痛的位置、特征、强度和频率的问题。Logistic回归分析了疼痛部位与泌尿系统症状之间的关系。使用SAS 8.2版（SAS Institute，卡里，NC，USA）进行分析，并认为在5%水平下具有显著性。平均年龄为45岁（SD 14岁）的589例（94%）患者报告了与泌尿系统症状相关的基线疼痛或不适。最常见的基线疼痛部位是下腹部（80%），尿道（74%）和腰痛（65%）也是常见报告。大多数患者描述其疼痛为间歇性，无论疼痛部位如何。大多数患者报告所有疼痛部位的中度疼痛强度。尿道、下背部和下腹部疼痛与泌尿系统症状之间存在统计学显著联系。IC患者报告在膀胱以外的几个部位疼痛，可能是由先前充分描述的IC和其他慢性盆腔疼痛综合征患者存在的盆底和腹壁肌筋膜异常引起的。
To describe the characteristics of pain experienced by patients with interstitial cystitis (IC) in terms of pain site, severity, and character, we performed a secondary analysis of data from the IC database (ICDB), which was a prospective, longitudinal, cohort study of IC patients. We analyzed the cross-sectional baseline data from 629 patients who had a completed baseline symptom questionnaire. Patients answered questions about whether they had pain or discomfort associated with urinary symptoms over the past 4 weeks and if so, about the location, characteristics, intensity, and frequency of their pain. Logistic regression examined associations between pain location and the presence of urinary symptoms. Analyses were performed using SAS version 8.2 (SAS Institute, Cary, NC, USA) and considered significant at the 5% level. Five hundred and eighty-nine (94%) patients with a mean age of 45 years (SD 14 years) reported baseline pain or discomfort associated with their urinary symptoms. The most common baseline pain site was lower abdominal (80%), with urethral (74%) and low back pain (65%) also commonly reported. The majority of patients described their pain as intermittent, regardless of the pain site. Most patients reported moderate pain intensity, across all pain sites. There was a statistically significant link between pain in the urethra, lower back, and lower abdomen, and urinary symptoms. Patients with IC report pain at several sites other than the bladder, possibly arising from the previously well-described myofascial abnormalities of pelvic floor and abdominal wall present in patients with IC and other chronic pelvic pain syndromes.