PSYCHIATRIC AND MEDICAL EFFECTS OF ANABOLIC-ANDROGENIC STEROID USE - A CONTROLLED-STUDY OF 160 ATHLETES
PSYCHIATRIC AND MEDICAL EFFECTS OF ANABOLIC-ANDROGENIC STEROID USE - A CONTROLLED-STUDY OF 160 ATHLETES
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DOI：
10.1001/archpsyc.1994.03950050035004
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发表时间：
1994-05-01
影响因子：
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通讯作者：
KATZ, DL
中科院分区：
文献类型：
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作者：
POPE, HG;KATZ, DL
背景：我们试图扩展一些初步发现，即合成代谢-雄激素在一些使用类固醇的运动员中会产生精神影响。方法：我们比较了88名使用类固醇的运动员和68名不使用类固醇的运动员，使用DSM-III-R的结构化临床访谈来诊断与类固醇使用(如果适用)和不使用类固醇相关的精神综合征。结果：服用类固醇的女性乳房发育更频繁，平均睾丸长度缩短，胆固醇-高密度脂蛋白比率高于非服用类固醇的女性。最引人注目的是，23%的类固醇使用者报告了与类固醇使用有关的主要情绪综合征-躁狂、轻躁狂或严重抑郁。使用类固醇的人在使用类固醇期间出现情绪障碍的频率明显高于没有使用类固醇的人(P
Background: We sought to expand on preliminary findings suggesting that anabolic-androgenic steroids produce psychiatric effects in some athletes who use them.Methods: We compared 88 athletes who were using steroids with 68 nonusers, using the Structured Clinical Interview for DSM-III-R to diagnose psychiatric syndromes occurring in association with steroid use (if applicable) and in the absence of steroid use. Demographic, medical, and laboratory measures were also performed.Results: Steroid users displayed more frequent gynecomastia, decreased mean testicular length, and higher cholesterol-high-density lipoprotein ratios than nonusers. Most strikingly, 23% of steroid users reported major mood syndromes-mania, hypomania, or major depression-in association with steroid use. Steroid users displayed mood disorders during steroid exposure significantly more frequently than in the absence of steroid exposure (P