Composition and sequence studies show that A/duck/Ukraine/1/63 haemagglutinin (Hav7) belongs to the Hong Kong (H3) subtype.
Composition and sequence studies show that A/duck/Ukraine/1/63 haemagglutinin (Hav7) belongs to the Hong Kong (H3) subtype.
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组成和序列研究表明，A/duck/Ukraine/1/63 血凝素 (Hav7) 属于香港 (H3) 亚型。
DOI：
10.1099/0022-1317-53-1-163
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Dopheide,TA
中科院分区：
文献类型：
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作者：
Ward,CW;Webster,RG;Inglis,AS;Dopheide,TA
来自禽流感病毒A/duck/Ukraine/1/63（Hav 7，Neq 2）的血凝素链HA 1和HA 2已进行氨基酸分析和N-末端测序。在酶促去除N-末端焦谷氨酸封闭基团后，HA 1（40个循环）和HA 2（43个循环）的自动测序仪分析显示Hav 7血凝素与人香港（H3）血凝素非常相似，包括在HA 1的N-末端存在特征性延伸的10个残基序列。这些发现以及两条链的氨基酸组成表明Hav 7血凝素在结构上与香港（H3）血凝素相似。
The haemagglutinin chains HA1 and HA2 from the avian influenza virus A/duck/Ukraine/1/63 (Hav7, Neq2) have been subjected to amino acid analysis and N-terminal sequencing. Automated sequenator analysis of HA1 (40 cycles), after enzymic removal of the N-terminal pyroglutamic acid blocking group, and HA2 (43 cycles) showed that the Hav7 haemagglutinin closely resembled the human Hong Kong (H3) haemagglutinins including the presence of the characteristic extended 10 residue sequence at the N-terminus of HA1. These findings, together with the amino acid compositions for both chains, demonstrate that the Hav7 haemagglutinin is structurally similar to the Hong Kong (H3) haemagglutinins.