Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum
Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum
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DOI:
10.1016/j.jep.2003.09.006
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发表时间:
2004-01-01
影响因子:
5.4
通讯作者:
Park, EH
中科院分区:
文献类型:
--
作者:
Song, YS;Kim, SH;Park, EH
Fresh fruit bodies of Ganoderma lucidum were extracted with 70%. ethanol at room temperature. The extract (GL) showed significant anti-angiogenic activity, which was detected using a chick embryo chorioallantoic membrane assay. GL significantly inhibited LPS-induced NO production in RAW 264.7 macrophages. These results support the anti-tumor effect of Ganoderma lucidum. (C) 2003 Elsevier Ireland Ltd. All rights reserved.