Reflex receptive fields for human withdrawal reflexes elicited by nonpainful and painful electrical stimulation of the foot sole
Reflex receptive fields for human withdrawal reflexes elicited by nonpainful and painful electrical stimulation of the foot sole
复制标题
DOI：
10.1016/s1388-2457(01)00485-0
复制
发表时间：
2001-04-01
影响因子：
4.7
通讯作者：
Arendt-Nielsen, L
中科院分区：
文献类型：
--
作者：
Andersen, OK;Sonnenborg, FA;Arendt-Nielsen, L
目的：研究人的戒断反射感受野(RRF)4种不同的电刺激强度，从低于痛阈值(PTH)到高达PTH强度的两倍(0.8x.1.2x.1.6x和2.0x PTH)。并记录坐着时的反射。刺激按随机顺序被传递到分布在脚底上的12个位置。胫骨前肌(TA)。记录腓肠肌内侧肌(GM)、股外侧肌(VL)和股二头肌(BF)反射。结果：与其他3种肌肉相比，TA肌的反射最强。背屈运动在距小腿关节远端占主导地位，对应于TA接受野区。当刺激强度从0.8x PTH增加到1.2x PTH和从1.2x PTH增加到1.6x PTH时，TA和GM的RRF扩大，这表明在TA收缩不宜退出反应的边界，反射阈值逐渐增加。对于BF和VL，未检测到RRF区域的边界。通过将反射大小整合到RRF中(即反射体积)，在所有被测试的4块肌肉中都可以看到逐渐增加的刺激强度的反射，其中以TA和GM最为明显。TA、GM和BF的主观疼痛强度与反射体积相关。结论：RRF中央的反射敏感度最高，而诱发反射所需的刺激强度向感受野边缘增加。在RRF内，刺激强度的增加会引起更强的反射。TA和GM的接受场大小的限制支持模块化的撤退反射组织。(C)2001爱思唯尔爱尔兰科学有限公司。保留所有权利。
Objectives: Human withdrawal reflex receptive fields (RRFs) were assessed for 4 different electrical stimulus intensities, ranging From below the pain threshold (PTh) to up to two times the PTh intensity (0.8 x. 1.2 x. 1.6 x, and 2.0 x PTh).Methods: Thirteen subjects participated. and the reflexes were recorded in a sitting position. The stimuli were delivered in random order to 12 positions distributed over the foot sole. Tibialis anterior (TA). gastrocnemius medialis (GM), vastus lateralis (VL), and biceps femoris (BF) reflexes were recorded. Further, knee and ankle joint angle changes were recorded.Results: The strongest reflexes were seen in the TA compared with the other 3 muscles. Dorsi-flexion dominated distal to the talocrural joint corresponding to the TA receptive field area. An expansion of the RRF for the TA and GM was seen when increasing the stimulus intensity from 0.8 x PTh to 1.2 x PTh and from 1.2 x PTh to 1.6 x PTh, indicating a gradually increasing reflex threshold towards the border, where TA contraction is inappropriate in a withdrawal reaction. For the BF and VL, the borders of the RRF areas were not detected. By integrating the reflex size within the RRF (i.e. the reflex volume), gradually increasing reflexes for increasing stimulus intensity were seen in all 4 muscles tested, most clearly in the TA and GM. The subjective pain intensity correlated to the reflex volume for the TA, GM, and BF.Conclusions: In conclusion, the highest reflex sensitivity was seen in the centre of the RRF, while the stimulus intensity needed for eliciting a reflex increased towards the receptive field border. Within the RRF, stronger reflexes were evoked for increasing stimulus intensity. The limit in the size of the receptive field size for the TA and GM supports a modular withdrawal reflex organisation. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.