Twelve months of electronic monitoring (MEMS®) in the Swedish COAST-study: A comparison of methods for the measurement of adherence in schizophrenia
Twelve months of electronic monitoring (MEMS®) in the Swedish COAST-study: A comparison of methods for the measurement of adherence in schizophrenia
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DOI：
10.1016/j.euroneuro.2013.11.013
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发表时间：
2014-02-01
影响因子：
5.6
通讯作者：
Waern, Margda
中科院分区：
文献类型：
--
作者：
Brain, Cecilia;Sameby, Birgitta;Waern, Margda
主要目的是比较 2008 年 10 月至 2011 年 6 月期间超过 12 个月的自然主义精神分裂症门诊患者队列中依从性的客观和主观测量。在一项自然主义前瞻性研究中，根据 DSM-IV 标准，对 117 名诊断为精神分裂症或精神分裂症样精神病的门诊患者的抗精神病药物依从性进行了监测。依从性由用药事件监测系统 (MEMS (R))、药丸计数、血浆水平以及患者、工作人员、精神科医生和密切知情者的评级来确定。血浆水平依从性测量反映了对药物治疗和实验室访问的依从性。 MEMS (R) 依从性和其他测量之间的关系用一致性指数和 kappa (K) 表示。不粘附 (MEMS (R)
The primary aim was to compare objective and subjective measures of adherence in a naturalistic cohort of schizophrenia outpatients over 12 months between October 2008 and June 2011. Antipsychotic medication adherence was monitored in 117 outpatients diagnosed with schizophrenia or schizophrenia-like psychosis according to DSM-IV criteria in a naturalistic prospective study. Adherence was determined by the Medication Event Monitoring System (MEMS (R)), pill count, plasma levels and patient, staff, psychiatrist and close informant ratings. The plasma level adherence measure reflects adherence to medication and to lab visits. Relationships between MEMS (R) adherence and other measures were expressed as a concordance index and kappa (K). Non-adherence (MEMS (R)