Tumor-induced osteomalacia

Tumor-induced osteomalacia
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肿瘤诱发的骨软化症

DOI:
10.1093/qjmed/hcac219
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发表时间:
2023
期刊:
QJM: An International Journal of Medicine
影响因子:
--
通讯作者:
Terada Y
Terada Y
中科院分区:
--
文献类型:
--
作者:
Aoyama N;Nishiyama M;Namba H;Ikeuchi M;Fujimoto S;Terada Y

文献摘要

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一名63岁的妇女2年前摔倒并肋骨骨折,次年腰椎骨折,行走困难。她因血清碱性磷酸酶升高和低磷血症而来我科就诊,并有全身疼痛的主诉。身高152厘米,体重49公斤。全血计数、肝功能、肾功能均在正常范围。血钙轻度下降[8.7 mg/dl(8.8-10.1)],血磷极低[1.1 mg/dl(2.4-4.3)],管状磷重吸收阈值
A 63-year-old woman fell and sustained a rib fracture 2 years ago, fractures of the lumbar spine the next year and had difficulty walking. She was referred to our department with raised serum alkaline phosphatase and hypophosphatemia and a complaint of systemic pain.Her height and body weight were 152 cm and 49 kg, respectively. Her complete blood count, liver function and renal function were in the normal range. Serum calcium was mildly decreased [8.7 mg/dl (8.8–10.1)], phosphate was extremely low [1.1 mg/dl (2.4–4.3)], tubular phosphorus reabsorption threshold