Irregular menses linked to vomiting in a nonclinical sample: Findings from the national eating disorders screening program in high schools
Irregular menses linked to vomiting in a nonclinical sample: Findings from the national eating disorders screening program in high schools
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DOI：
10.1016/j.jadohealth.2007.11.139
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发表时间：
2008-05-01
影响因子：
7.6
通讯作者：
Jacobs, Douglas
中科院分区：
文献类型：
--
作者：
Austin, S. Bryn;Ziyadeh, Najat J.;Jacobs, Douglas
目的：利用在美国高中进行的饮食失调筛查倡议的数据，我们检查了青春期女性非临床样本中呕吐频率和月经不规律之间的关系。方法：对2000年参加国家饮食失调筛查计划的美国高中学生进行自我报告问卷调查。问卷内容包括：过去3个月内用于控制体重的呕吐次数、其他饮食失调症状、月经次数、身高和体重。使用来自2791名女孩的数据进行多变量回归分析，以估计与呕吐频率相关的月经不规则（定义为月经少于每月一次）的风险，并根据其他饮食失调症状、体重状况、年龄、种族/民族和学校群体进行调整。结果：为了控制体重而每月呕吐1 - 3次的女孩出现月经不规律的可能性是没有为了控制体重而呕吐的女孩的1.5倍（风险比[RR] = 1.6； 95%可信区间[CI] = 1.2-2.2），而每周呕吐1次或更频繁的女孩出现月经不规律的可能性是没有为了控制体重而呕吐的女孩的3倍以上（RR = 3.2; 95% CI = 2.3-4.4）。即使超重和体重不足的参与者被排除在外，呕吐控制体重仍然是月经不规律的一个强有力的预测因素。结论：我们的研究进一步证明，呕吐可能对青春期女孩的激素功能有直接影响，而为了控制体重而呕吐可能是饮食失调的一个特别有害的组成部分。(C) 2008年青少年医学学会。版权所有。
Purpose: Using data from an eating disorders screening initiative conducted in high schools across the United States, we examined the relationship between vomiting frequency and irregular menses in a nonclinical sample of adolescent females.Methods: A self-report questionnaire was administered to students from U.S. high schools participating in the National Eating Disorders Screening Program in 2000. The questionnaire included items on frequency of vomiting for weight control in the past 3 months, other eating disorder symptoms, frequency of menses, height, and weight. Multivariable regression analyses were conducted using data from 2791 girls to estimate the risk of irregular menses (defined as menses less often than monthly) associated with vomiting frequency, adjusting for other eating disorder symptoms, weight status, age, race/ethnicity, and school clusters.Results: Girls who vomited to control their weight one to three times per month were one and a half times more likely (risk ratio [RR] = 1.6; 95% confidence interval [CI] = 1.2-2.2), and girls who vomited once per week or more often were more than three times more likely (RR = 3.2; 95% CI = 2.3-4.4), to experience irregular menses than were girls who did not report vomiting for weight control. Vomiting for weight control remained a strong predictor of irregular menses even when overweight and underweight participants were excluded.Conclusions: Our study adds to the evidence that vomiting may have a direct effect on hormonal function in adolescent girls, and that vomiting for weight control may be a particularly deleterious component of eating disorders. (C) 2008 Society for Adolescent Medicine. All rights reserved.