Direction of motion discrimination after early lesions of striate cortex (V1) of the macaque monkey.
Direction of motion discrimination after early lesions of striate cortex (V1) of the macaque monkey.
复制标题
猕猴纹状皮层（V1）早期损伤后的运动方向辨别。
DOI：
10.1073/pnas.98.1.325
复制
发表时间：
2001
影响因子：
11.1
通讯作者：
Gross,CG
中科院分区：
文献类型：
--
作者：
Moore,T;Rodman,HR;Gross,CG
先前的研究已经证实，人类和猴子的纹状皮层受损，能够检测和定位在由此产生的暗点明亮的目标。猴子的电生理学证据表明，残余视力也可能包括对视觉运动方向的敏感性。我们测试了是否猕猴长期病变的纹状体皮质（V1），持续在婴儿期，可以区分视觉刺激的运动方向的基础上。 三只在婴儿期单侧纹状体皮质损伤的猴子在损伤后2-5年进行了运动方向辨别任务的测试。每只猴子都被训练对一个移动的点进行扫视运动，或者保持这种眼球运动，这取决于连贯的随机点显示中的运动方向。 对于较小的运动显示器，猴子无法检测或区分暗点内的运动，尽管它们可以区分静态刺激和运动。然而，每只猴子都能够在运动刺激较大时辨别运动方向，但仍局限于暗点。结果表明，婴儿纹状体皮层损伤后的恢复包括对视觉运动方向的敏感性。
Previous studies have established that humans and monkeys with damage to striate cortex are able to detect and localize bright targets within the resultant scotoma. Electrophysiological evidence in monkeys suggests that residual vision also might include sensitivity to direction of visual motion. We tested whether macaque monkeys with longstanding lesions of striate cortex (V1), sustained in infancy, could discriminate visual stimuli on the basis of direction of motion. Three monkeys with unilateral striate cortex lesions sustained in infancy were tested 2–5 years postlesion on a direction of motion discrimination task. Each monkey was trained to make saccadic eye movements to a field of moving dots or to withhold such eye movements, depending on the direction of motion in a coherent random dot display. With smaller motion displays, monkeys were unable to detect or discriminate motion within the scotoma, although they could discriminate moving from static stimuli. Yet, each monkey was able to discriminate direction of motion when the motion stimulus was larger, but still confined to the scotoma. The results demonstrate that the recovery after infant damage to striate cortex includes some sensitivity to direction of visual motion.