STAPHYLOCOCCUS-AUREUS IN LESIONS OF ATOPIC-DERMATITIS
STAPHYLOCOCCUS-AUREUS IN LESIONS OF ATOPIC-DERMATITIS
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DOI：
10.1111/j.1365-2133.1974.tb06447.x
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发表时间：
1974-01-01
影响因子：
10.3
通讯作者：
KLIGMAN, AM
中科院分区：
文献类型：
--
作者：
LEYDEN, JJ;MARPLES, RR;KLIGMAN, AM
从50例慢性斑块患者和20例特应性皮炎渗出性病变患者中获得定量需氧培养物。前者金黄色葡萄球菌检出率为90%，密度超过1 × 106/cm 2的占45%。在渗出形式，葡萄球菌。金黄色葡萄球菌的平均密度为14 × 106个/cm ~ 2。葡萄球菌金黄色葡萄球菌不仅是病变中的优势微生物，而且在附近的临床正常皮肤中也是优势微生物。尽管这些数字很高，但缺乏感染的临床症状。全身和局部抗生素治疗导致葡萄球菌显著减少。金黄色葡萄球菌密度。金黄色葡萄球菌可加重基础病变并成为葡萄球菌的来源。接触者的金黄色葡萄球菌感染。
Quantitative aerobic cultures were obtained from fifty patients with chronic plaques, and from twenty with exudative lesions of atopic dermatitis. In the former, Staphylococcus aureus was isolated from 90% and the density exceeded 1 × 106/cm2in 45% of the samples. In the exudative form, Staph. aureus was recovered in every case with a mean density of 14 × 106organisms per cm2. Staph. aureus was the dominant organism not only in the lesions but in nearby clinically normal skin. Despite these high numbers, clinical signs of infection were lacking. Systemic and topical antibiotic therapy pro‐duced a profound decrease in Staph. aureus density.It is proposed that high numbers of Staph. aureus may aggravate the underlying lesion and be the source ofStaph. aureusinfections in contacts.