Effect of Maternal Obesity on the Ultrasound Detection of Anomalous Fetuses
Effect of Maternal Obesity on the Ultrasound Detection of Anomalous Fetuses
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DOI：
10.1097/aog.0b013e3181a1d2f5
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发表时间：
2009-05-01
影响因子：
7.2
通讯作者：
Twickler, Diane M.
中科院分区：
文献类型：
--
作者：
Dashe, Jodi S.;McIntire, Donald D.;Twickler, Diane M.
目的：评估孕中期标准和针对性超声检查中母亲体型对检测胎儿主要结构异常的影响。方法：这是一项为期 5 年期间接受超声检查的 18 至 24 周妊娠的回顾性队列研究。无论预期的超声检测结果如何，如果相关器官系统出现重大异常，则认为检测到异常胎儿。使用前瞻性维护的数据库来验证异常情况。体重指数 (BMI) 基于第一次产前检查时的体重。 结果：对低风险妊娠进行了 10,112 次标准检查，对有高风险指征或在标准超声检查中发现异常的妊娠进行了 1,098 次针对性检查。异常胎儿的检出率随着体重指数的增加而减少。对于正常 BMI、超重和 1、11 和 III 级肥胖，标准超声检查的检出率分别为 66%、49%、48%、42% 和 25%，而靶向超声检查的检出率分别为 97%、91%、75%、88% 和 75%，两者均 P
OBJECTIVE: To estimate the effect of maternal habitus on detection of fetuses with major structural anomalies during second-trimester standard and targeted ultrasound examinations.METHODS: This was a retrospective cohort study of pregnancies 18 to 24 weeks that underwent ultrasonography over a 5-year period. An anomalous fetus was considered detected if a major abnormality of the relevant organ system was identified, regardless of the anticipated ultrasound detection. Anomalies were verified using a prospectively maintained database. Body mass index (BMI) was based on weight at first prenatal visit.RESULTS: There were 10,112 standard examinations in low-risk pregnancies and 1,098 targeted examinations in pregnancies with either high-risk indications or with an abnormality detected during standard ultrasonography. Detection of anomalous fetuses decreased with increasing BMI. For normal BMI, overweight, and class 1, 11, and III obesity, detection with standard ultrasonography was 66%, 49%, 48%, 42%, and 25%, respectively, and with targeted ultrasonography, 97%, 91%, 75%, 88%, and 75%, respectively, both P