Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data
Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data
复制标题
DOI：
10.1016/s0378-4274(02)00041-3
复制
发表时间：
2002-05-10
影响因子：
3.5
通讯作者：
Heberer, T
中科院分区：
文献类型：
--
作者：
Heberer, T
药物活性化合物(PHAC)在水环境中的发生和去向已被公认为环境化学中的新兴问题之一。在奥地利、巴西、加拿大、克罗地亚、英国、德国、希腊、意大利、西班牙、瑞士、荷兰和美国进行的一些调查中，在水环境中检测到80多种化合物、药物和几种药物代谢物，在污水进水和出水样品以及城市污水处理厂(STP)下游的几个地表水中发现了几种不同处方类别的PHAC，浓度达到MUG/L水平。研究表明，一些源于人类治疗的PHAC在市政STP中并未完全消除，因此作为污染物排放到接收水中。在补给条件下，环丙沙酸、卡马西平、扑草酮或碘化造影剂等极性PHAC可以渗入底土，在德国的几个地下水样本中也检测到了PHAC。然而，在被垃圾填埋场渗滤液或制造残留物污染的地下水中也报告了PHAC的阳性结果。到目前为止，在饮用水样本中也检测到微量PHAC的情况只有少数几例。(C)2002爱思唯尔科学爱尔兰有限公司。保留所有权利。
The occurrence and fate of pharmaceutically active compounds (PhACs) in the aquatic environment has been recognized as one of the emerging issues in environmental chemistry. In some investigations carried out in Austria, Brazil, Canada, Croatia, England, Germany, Greece, Italy, Spain, Switzerland, The Netherlands, and the U.S., more than 80 compounds, pharmaceuticals and several drug metabolites, have been detected in the aquatic environment, Several PhACs From various prescription classes have been found at concentrations up to the mug/l-level in sewage influent and effluent samples and also in several surface waters located downstream from municipal sewage treatment plants (STPs). The studies show that some PhACs originating from human therapy are not eliminated completely in the municipal STPs and are, thus, discharged as contaminants into the receiving waters. Under recharge conditions, polar PhACs Such as clofibric acid, carbamazepine, primidone or iodinated contrast agents can leach through the subsoil and have also been detected in several groundwater samples in Germany. Positive findings of PhACs have, however, also been reported in groundwater contaminated by landfill leachates or manufacturing residues. To date, only in a few cases PhACs have also been detected at trace-levels in drinking water samples. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.